Author Topic: The War with Medical Fascism  (Read 58762 times)


Crafty_Dog

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Immune system overload
« Reply #301 on: January 11, 2022, 08:09:33 PM »
Repeat Covid Booster Shots Risk Overloading Immune System, EU Regulators Warn - Bloomberg

 

If you can't see it here is Berenson's summary:

European drug regulators abruptly reverse course on boosters (substack.com)


Crafty_Dog

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Whoa!!! The Vaxxes and neurodegenerative disease
« Reply #303 on: January 12, 2022, 06:38:47 AM »
By Natali _ Mis/Shutterstock
By Natali _ Mis/Shutterstock
HEALTH NEWS
SARS-COV-2 Vaccines and Neurodegenerative Disease
By Stephanie Seneff and GreenMedInfo January 11, 2022 Updated: January 11, 2022biggersmaller Print
Since December 2021, when several novel unprecedented vaccines against SARS-CoV-2 began to be approved for emergency use, there has been a worldwide effort to get these vaccines into the arms of as many people as possible as fast as possible. These vaccines have been developed “at warp speed,” given the urgency of the situation with the COVID-19 pandemic. Most governments have embraced the notion that these vaccines are the only path towards resolution of this pandemic, which is crippling the economies of many countries.

Thus far, there are four different vaccines that have been approved for emergency use for protection against COVID-19 in the US and/or Europe. Two (the Moderna vaccine and the Pfizer/BioNTech vaccine) are based on mRNA technology, whereas the other two (produced by Johnson & Johnson and AstraZeneca) are based on a double-stranded DNA recombinant viral vector. The mRNA vaccines contain only the code for the SARS-CoV-2 envelope spike protein, whereas the DNA-based vaccines both contain an adenovirus viral vector that has been augmented with DNA that codes for the SARS-CoV-2 spike protein. The DNA-based vaccines have a certain advantage over the RNA-based vaccines in that they do not have to be stored at deep-freeze temperatures, because double-stranded DNA is much more stable than single-stranded RNA. But a disadvantage is that those who have been exposed to natural forms of the adenovirus have antibodies to the virus that will likely block the synthesis of the spike protein, and therefore not afford protection against SARS-CoV-2.

In this regard, the AstraZeneca (AZ) vaccine has a slight advantage over the Johnson & Johnson (J&J) vaccine because the virus normally infects chimpanzees rather than humans, so fewer people are likely to have been exposed to it. On the other hand, several studies have shown that viruses that normally infect one species can cause tumors if they are injected into a different species. For example, a human adenovirus injected into baboons caused retinoblastoma (cancer of the eye) in the baboons . So, it can’t be ruled out that the AZ vaccine could lead to cancer.

People don’t realize that these vaccines are vastly different from the many childhood vaccines we are now used to getting early in life. I find it shocking that the vaccine developers and the government officials across the globe are wrecklessly pushing these vaccines on an unsuspecting population. Together with Dr. Greg Nigh, I recently published a peer-reviewed paper on the technology behind the mRNA vaccines and the many potentially unknown consequences to health . Such unprecedented vaccines normally take twelve years to develop, with only a 2% success rate, but these vaccines were developed and brought to market in less than a year. As a consequence, we have no direct knowledge of any effects that the vaccines might have on our health over the long term. However, knowledge about how these vaccines work, how the immune system works and how neurodegenerative diseases come about can be brought to bear on the problem in order to predict potential devastating future consequences of the vaccines.

The mRNA in these vaccines codes for the spike protein normally synthesized by the SARS-CoV-2 virus. However, both the mRNA and the protein it produces have been changed from the original version in the virus with the intent to increase rate of production of the protein in an infected cell and the durability of both the mRNA and the spike protein it codes for. Additional ingredients like cationic lipids and polyethylene glycol are also toxic with unknown consequences. The vaccines were approved for emergency use based on grossly inadequate studies to evaluate safety and effectiveness.

Our paper showed that there are several mechanisms by which these vaccines could lead to severe disease, including autoimmune disease, neurodegenerative diseases, vascular disorders (hemorrhaging and blood clots) and possibly reproductive issues. There is also the risk that the vaccines will accelerate the emergence of new strains of the virus that are no longer sensitive to the antibodies produced by the vaccines. When people are immune compromised (e.g., taking chemotherapy for cancer), the antibodies they produce may not be able to keep the virus in check because the immune system is too impaired. Just as in the case of antibiotic resistance, new strains evolve within an infected immune-compromised person’s body that produce a version of the spike protein that no longer binds with the acquired antibodies. These new strains quickly come to dominate over the original strain, especially when the general population is heavily vaccinated with a vaccine that is specific to the original strain. This problem is likely going to necessitate the repeated rollout of new versions of the vaccine at periodic intervals that people will have to receive to induce yet another round of antibody production in an endless game of cat and mouse.

Like the mRNA vaccines, the DNA vaccines are based on novel biotech gene editing techniques that are brand new, so they too are a massive experiment unleashed on a huge unsuspecting population, with unknown consequences. Both DNA vector vaccines have been associated with a very rare condition called thrombocytopenia, in which platelet counts drop precipitously, resulting in system-wide blood clots and a high risk of cerebral hemorrhaging [5]. This is likely due to an autoimmune reaction to the platelets, and it comes with a high risk of mortality. In the case of the AZ vaccine, this has caused over 20 European countries to temporarily pause their vaccination programs [6]. And the United States called a temporary halt on the J&J vaccine.

Even experts don’t really understand the mechanism as of now, although a fascinating theory to explain this depends on the fact that DNA vector vaccines require the DNA to be copied into RNA in the nucleus, and this presents the possibility of producing an incomplete copy, generated through “splice variants,” that is missing the code for attaching to the membrane. These soluble partial sequences wander off to other parts of the body and bind to ACE2 receptors throughout the vasculature. Antibodies to these ACE2-bound partial spike fragments cause an acute inflammatory response that results in disseminated intravascular coagulation (DIC).

How to Make an Adenovirus DNA Vector Vaccine
The adenovirus vaccines are created through techniques that the average citizen can’t possibly fathom could even exist. For the AZ vaccine, the bulk of the DNA in the vaccine codes for the various proteins that are needed by a strain of adenovirus that mainly infects chimpanzees and causes cold-like symptoms. However, it is not a “normal” version of this cold virus. First of all, it has been stripped of certain genes that it needs in order to replicate, and for this reason it is referred to as an “adenovirus vector.” This defect, it is argued, keeps it from actually infecting the vaccinated patient. Secondly, it is modified, through gene editing techniques, to create a recombinant version of the virus that contains the complete coding sequence for the SARS-CoV-2 spike protein, spliced into its DNA sequence – the same protein that the RNA vaccines code for. The recombinant DNA is a linear double-stranded DNA sequence where proteins from two different species are integrated through gene editing.

Since this virus can’t proliferate, it is difficult to manufacture large quantities of it. But they solved this problem by making use of a genetically modified version of a human cell line, called HEK (human embryonic kidney) 293 cells, where the human cell’s DNA was transfected long ago with fragments of the genome of an adenovirus – conveniently providing the defective recombinant virus with the missing proteins it needs to be able to proliferate. Within a culture of these HEK 293 cells, the virus can replicate, assisted by the proteins that are produced by the host cells. The HEK 293 cells originally came from a kidney of an aborted fetus, and it has been maintained in culture ever since the 1970s, because it was modified to become immortal, with the help of the adenovirus. Although it was obtained from a kidney, it is not a kidney cell. In fact, it has many properties that are characteristic of a neuronal stem cell. The fact is, they don’t really know what kind of cell it is. The ability of a cell line to survive indefinitely is a feature of tumor cells. Although the vaccine is “purified” during the processing, there is no guarantee that it is not contaminated with remnants from the host cells, i.e., human DNA of a neuronal tumor cell line. It does not seem like a good idea to inject the DNA of a human tumor cell into anyone.

The J&J vaccine has a very similar manufacturing process, except with a different adenovirus strain and a different human host cell. For J&J, the host cell is another fetal cell line harvested long ago and made immortal through the incorporation of adenovirus genes into the host human genome. This cell line was taken from the retina of the eye of the fetus.

The Spike Protein is Toxic
The COVID-19 vaccines are all based on supplying genetic code to produce the spike protein that is the main constituent of the SARS-CoV-2 protein cage that encloses its RNA contents. Both the DNA vector and the RNA vaccines induce the vaccine-infected cell to manufacture many copies of the spike protein according to the code. Through experimentation, researchers have determined that the spike protein is toxic even when introduced all by itself. In a revealing experiment, researchers injected spike protein into hamsters, and found that it was taken up by endothelial cells lining the blood vessels, via ACE2 receptors. This caused a downregulation of ACE2, which had significant effects on the metabolic policy in the cells. In particular, it inhibited the synthesis of mitochondria, and caused the existing mitochondria to fragment. Mitochondria are the organelles in the cell that produce large quantities of ATP (the energy currency of cells) by oxidizing nutrients, while consuming oxygen and producing water and carbon dioxide. The spike protein reduced the production of ATP by mitochondria and increased glycolysis — the alternative, much less efficient, way to produce ATP without using oxygen. This metabolic change towards getting energy through glycolysis is a characteristic feature of cancer cells and of neurons in neurodegenerative diseases such as Alzheimer’s.

In another experiment, researchers showed that spike protein can cross the blood-brain barrier in mice and be taken up by neurons throughout the brain. This too is likely mediated by ACE2 receptors (which neurons also produce). These same researchers also showed that spike protein administered in the nose was able to reach the brain by traveling along the olfactory nerve. When they induced inflammation in the brain through exposure to lipopolysaccharide (LPS), they saw an increased uptake of spike protein into the brain, which they hypothesized was caused by increased leakiness in the barrier. As you will see, these points become important when we later consider what happens following a SARS-CoV-2 vaccine, which is designed to induce inflammation.

Many people suffering from COVID-19 have experienced symptoms characteristic of the central nervous system such as headache, nausea, dizziness, fatal brain blood clots and encephalitis. In an advanced 3D microfluid model of the human BBB, researchers in the United States showed that the spike protein by itself disrupts the blood brain barrier by inducing an inflammatory state, and they proposed that this could be the source of such symptoms.

A published preprint found widespread expression of ACE2 in many parts of the brain. ACE2 was expressed in astrocytes, pericytes (cells that wrap around the endothelial cells lining capillary walls) and in endothelial cells — and all of these are key components of the blood-brain barrier. Perhaps of even greater concern is that ACE2 was highly expressed in the substantia nigra, a brain-stem nucleus where damaged dopaminergic neurons lead to Parkinson’s disease.

Bell’s Palsy, Autism and Parkinson’s Disease
In a paper aptly titled, “Is COVID-19 a Perfect Storm for Parkinson’s Disease?” researchers made a strong case for the possibility that we will see an increase in Parkinson’s disease in the future, due to the COVID-19 pandemic. They refer to three separate cases where acute Parkinsonism developed shortly after a COVID-19 infection. They proposed that systemic inflammation caused by severe COVID-19 could trigger neuroinflammation in the substantia nigra, killing off dopaminergic neurons. These neurons express high levels of the ACE2 receptor, making them highly vulnerable to the spike protein. A viral infection is known to upregulate α-synuclein, which, in high concentrations, forms soluble oligomers that then precipitate out as fibrils and accumulate within “Lewy bodies” that are tightly linked to Parkinson’s disease. Further corroboration of this idea comes from a paper which demonstrated that an infection with SARS-CoV-2 causes brain inflammation in macaques and induces the formation of Lewy bodies.

Parkinson’s disease is the second most common neurodegenerative disorder and the most common neurodegenerative motor disorder. The root cause of nearly 90% of cases remains unknown, but it has been theorized that viral infections are often involved. It can be argued that the loss of a sense of smell and/or taste in association with COVID-19 is a sign of a Parkinsonian link, since this symptom is also an early sign of Parkinson’s disease.

The mRNA vaccines appear to disrupt the body’s ability to keep latent viruses from “waking up” and causing disease symptoms. This observation is based on the fact that shingles and facial palsy (Bell’s palsy) are being commonly reported in side-effect reports in the FDA’s Vaccine Adverse Event Reporting System. As of May 21, 2021, over 2500 reports of Bell’s palsy following COVID-19 vaccines had appeared in VAERS. A primary cause of Bell’s palsy is the activation of latent viral infections, most notably Herpes simplex and Varicella zoster, Varicella zoster is also the virus responsible for shingles.

While Bell’s palsy usually resolves over time, there can be some serious longer-term consequences. Pregnant women who are diagnosed with active herpes infections during pregnancy have a 2-fold increased risk of having an autistic male child from that pregnancy. This should make a pregnant woman hesitate to get a SARS-CoV-2 vaccine. Bell’s palsy can also be a risk factor for Parkinson’s disease much later in life. A study on nearly 200 Parkinson’s disease patients compared with age- and gender-matched controls found that six of the Parkinson’s patients had had an earlier diagnosis of Bell’s palsy, whereas none of the control patients had. There’s also a link between autism and Parkinson’s disease. A study on autistic adults over 39 years old found that one third of them had symptoms that meet the criteria for a Parkinson’s diagnosis.

Prion Diseases
Prion diseases are a group of severe neurodegenerative diseases that are caused by misfolded prion proteins. The most common prion disease in humans is the always-fatal sporadic Creutzfeldt-Jakob disease (CJD), which accounts for more than 85% of the cases. Prion diseases are more specifically called transmissible spongiform encephalopathies (TSEs), and infection can spread through exposure to misfolded proteins as “infective” agents, without requiring a live pathogen. PrP is the name given to the specific prion protein associated with these TSEs. Misfolded PrP proteins act as a seed or catalyst that then recruits other molecules of PrP to misfold in the same way and glom together into pathogenic fibrils.

MADCOW, the disease that affected a large number of cows in Europe beginning in the 1990s, is probably the best-known TSE. While eating beef from an infected animal is a very rare risk factor, most cases of Creutzfeldt-Jakob disease occur for unknown reasons, and no other risk factors have been identified. A study based in Switzerland confirmed that many patients who died of Creutzfeldt-Jakob disease had detectable levels of a prion protein in their spleen and muscles, in addition to the olfactory lobe and the central nervous system. More generally, diseases involving misfolded PrPs have consistently been found to involve an initial early phase of prion replication in the spleen which happens long before overt symptoms appear. This point becomes important when we consider whether the COVID-19 vaccines might cause prion diseases.

PrP has a unique feature that it contains multiple copies of a characteristic motif in its amino acid sequence that is called a “GxxxG” motif, also known as a “glycine zipper”. These proteins normally fold into a characteristic shape called an alpha helix, which allows the protein to penetrate the plasma membrane. The glycines in the zipper motif play an essential role in cross-linking and stabilizing alpha helices. This glycine zipper motif is also a common characteristic of many transmembrane proteins (proteins that cross the membrane of the cell).

Indeed, the coronavirus spike protein has a GxxxG motif in its transmembrane domain (specifically, GFIAG — glycine, phenylalanine, isoproline, alanine, glycine). There is a platform called “Uniprot” where you can look up the sequence of specific proteins. The Uniprot entry for the SARS-CoV-2 spike protein has five glycine zipper sequences altogether. According to J. Bart Classen, the SARS-CoV-2 spike protein has the ability “to form amyloid and toxic aggregates that can act as seeds to aggregate many of the misfolded brain proteins and can ultimately lead to neurodegeneration.”

Many neurodegenerative diseases have been linked to specific proteins that have prion-like properties, and these diseases are characterized as protein-misfolding diseases or proteopathies. Like PrP, prion-like proteins become pathogenic when their alpha helices misfold as beta sheets, and the protein is then impaired in its ability to enter the membrane. These diseases include Alzheimer’s, amyotrophic lateral sclerosis (ALS), Huntington’s disease and Parkinson’s disease, and each of these is associated with a particular protein that misfolds and accumulates in inclusion bodies in association with the disease. We already saw that Parkinson’s disease is characterized by Lewy bodies in the substantia nigra that accumulate misfolded α-synuclein.

Glycines within the glycine zipper transmembrane motifs in the amyloid beta precursor protein (APP) play a central role in the misfolding of amyloid beta linked to Alzheimer’s disease (Decock et al., 2016). APP contains a total of four GxxxG motifs (one fewer than the spike protein).

A case study presented the case of a man who developed CKD simultaneously with symptomatic COVID-19. The authors proposed that infection with SARS-CoV-2 precipitates or accelerates neurodegenerative diseases. A theoretical paper published by researchers in India showed that the spike protein binds to a number of aggregation-prone prion-like proteins, including amyloid beta, α-synuclein, tau, PrP and TDP-43. They argued that this could initiate aggregation of these proteins in the brain, leading to neurodegeneration.

Tracing the Vaccine Trail to the Spleen
It is important to understand what happens to the contents of a vaccine after it is injected into the arm. Where does it travel in the body, and what does it do in the places where it settles in?

Vaccine developers are keen to know whether the vaccine induces a strong immune response, reflected in high antibody production against the spike protein, in the case of COVID-19 vaccines. And to do this, they need to trace its movement in the body.

CD8+ T-cells are cytotoxic immune cells that can kill cells that are infected with a virus. They detect an immune complex with viral proteins that are exposed on the surface of an infected cell. A study on an adenovirus-vector based vaccination of mice used clever methods to produce a marker that could track the activity of CD8+ T-cells in the lymph system and the spleen, in the days following vaccination. It can be inferred that immune cells (antigen-presenting cells, where the “antigen” is the spike protein) were initially present at the arm muscle injection site and synthesized the virus spike protein from the vaccine DNA code, exposing it on their surface. Once activated by the foreign protein, they translocated into the draining lymph nodes and finally made their way to the spleen via the lymph system. The CD8+ T-cells are idly waiting within the lymphatics until they spot an infected immune cell. Researchers could detect activation of CD8+ immune cells over time and inferred that this was caused by the arrival of the contents of the vaccine to the site where these immune cells reside. Activated CD8+ T-cells first appeared in the draining lymph nodes, but after five days began to show up in the spleen. Their numbers there peaked sharply by 12 days and then remained high with a slow decay up to 47 days, when the researchers stopped looking. What this means is that the vaccine is picked up by antigen-presenting cells at the injection site and carried to the spleen via the lymph system. The carrier cells then hang out in the spleen for a long time. And this is where the danger lies in terms of the potential to cause prion disease.

In the paper that Greg Nigh and I published recently on the mRNA vaccines, we argued that the mRNA vaccines are rather perfectly set up to produce a very dangerous situation in the spleen that is poised to launch a prion disease. Given the fact that the DNA vector vaccines also end up concentrated in the spleen, I think that the same thing holds true for them as well. The spleen is where the action is for seeding misfolded prion proteins. The vaccine-infected cells have been programmed to produce large amounts of spike proteins. Prion proteins misfold into damaging beta-sheet oligomers when there are too many of them in the cytoplasm. Might the spike protein do the same?

Three out of the four COVID-19 vaccines currently on the market in the U.S. and Europe (Pfizer, Moderna, and J&J) use a genetic code for the spike protein that has been slightly tweaked, in order to produce a more potent antibody response. Normally, after binding to the ACE2 receptor, the spike protein spontaneously changes its shape in a dramatic way in order to fuse with the membrane of the cell. In a Web publication, Ryan Cross described this action very graphically based on a spring-like model, as follows: “When the spike protein binds to a human cell, that spring is released, and the two helices and the loop straighten into one long helix that harpoons the human cell and pulls the virus and human membranes close together until they fuse.” As Cross explains, through trial and error, but taking structural information into account, researchers came up with the idea of swapping out two adjacent amino acids for prolines in the membrane fusion domain in order to stabilize the shape of the spike protein in its pre-fusion form. In this form, it exposes critical antigenic areas, and this assures more rapid formation of matching antibodies, the only goal of the vaccine design. This also prevents the protein from fusing with the plasma membrane of a host cell. I’d imagine that the spike protein attaches to the ACE2 receptor and then gets stuck there, like a sitting duck. But a worrisome thought is whether this open state, not fused with the membrane, might more closely resemble the shape of a misfolded prion-like protein like amyloid beta than does the collapsed shape it needs to go into the membrane?

Tetz and Tetz have argued in a published online preprint that prion-like domains in the spike protein enable higher affinity for the ACE2 receptor, making the virus more virulent than its earlier cousins. These same authors published an earlier peer-reviewed journal paper where they observed that many other viruses have proteins in their coat that have distinct features of prion proteins.

Germinal Centers and Parkinson’s Disease
Germinal centers in the spleen are a primary factory where antibodies against specific antigens (such as the spike protein) are manufactured and perfected. Makers of the mRNA vaccines were pleased to see that antigen-presenting cells (mainly dendritic cells), originally attracted to the site of the injection, take up the mRNA particles and then migrate via the lymph system to the spleen in high numbers and induce high levels of antibody production in these germinal centers.

Unfortunately, these same germinal centers are a primary site for the initiation of a process of producing and distributing misfolded prion proteins, often seeded by viral proteins, and triggered by an acute inflammatory response.

B cells, also known as B lymphocytes, are a type of immune cell that is the key player in the process that leads to the production of specific antibodies to a foreign antigen [38]. They originate from precursor cells in the bone marrow, and then migrate to the spleen and other lymphoid organs, where they bind to antigens presented to them by antigen-presenting cells, such as the dendritic cells. A maturation process beginning with a multipotent progenitor B cell ends with a mature “memory” B cell that has gone through a complex process to perfect its antibody production process to specifically match the antigen it has been assigned to (e.g., the spike protein). B cells also go through another process called class switching, which changes the type of antibody they produce from one class to another, without changing its specificity to the antigen.

Antibodies are also known as immunoglobulins (Igs), and the possible classes include IgM, IgG, IgA and IgE. IgM is the first immunoglobulin class that is produced (primarily in the spleen), and it is converted into IgG through class switching. IgG is the dominant class in the blood, making up 75% of the serum antibodies, and it is essential for clearing infections in the tissues. Long-lived mature memory B cells cruise the blood stream looking for any appearances of the antigen they have been assigned to, but they are useless for anything else. When the virus they’ve been trained to match mutates to the point where their antibodies no longer match well, they become useless even for the disease they’re trained to fight.

When mice are injected with PrP in the abdomen (intraperitoneal injection), the PrP shows up very quickly in the spleen. From there, the PrP travels along the spinal cord and the vagus nerve to reach the brain, causing prion disease [39]. As we will soon see, α-synuclein, the prion-like protein linked to Parkinson’s disease, also makes its way to the brain from the spleen along the vagus nerve. The mRNA vaccines set up perfect conditions in the spleen for the formation and distribution of conglomerates made up of misfolded α-synuclein, PrP and spike protein.

While α-synuclein causes neurodegenerative disease when it misfolds, in its normal shape it is an active participant in the immune response. α-Synuclein facilitates the processes that lead to antibody production in response to foreign antigens. Dendritic cells express α-synuclein, and it is upregulated (over-expressed) in response to stressors, such as the mRNA, the cationic lipids, and the PEG in the mRNA vaccines. Much can be learned by studying mice that have been genetically engineered to have a defective version of α-synuclein. These mice have a decreased capacity to clear pathogens through phagocytosis, and an impairment in the ability to generate B cells from precursor stem cells. They also had a four-fold reduction in progenitor B cells in the bone marrow. The amount of immunoglobulin G was reduced compared to wildtype, suggesting impaired class switching. Altogether, they are unable to mount an effective immune response to antigens, whether they come from a natural threat or a vaccine.

Dendritic cells under stress accumulate prion proteins and release them into small lipid particles called exosomes, which are then distributed throughout the body, either along nerve fibers or in the general circulation. There is reason to believe that these vaccines will accelerate the release of exosomes containing misfolded prion-like spike proteins that are being produced in large amounts under instruction from the vaccines. These spike proteins will act as seeds to cause α-synuclein and PrP to also misfold and form toxic oligomers together with the spike protein, which are released into the extracellular space as exosomes. These exosomes, released under the severe stress conditions induced by the vaccine, then carry prion proteins into the brain along the vagus nerve, to initiate prion diseases.

Impaired Immune Response due to Over-vaccination
A characteristic of the elderly is an impaired ability to mount antibodies against new pathogenic threats, and this is reflected in a failure to generate protective antibodies in response to vaccination. It has been demonstrated in experiments with mice that aged mice have an overabundance of long-lived memory (antigen-experienced) B cells, and this is paired with an inability to generate new B cells from progenitor cells in the bone marrow, as well as impairment in the process of refinement of the antibody response in germinal centers in the spleen and the associated class switching that produces effective IgG antibodies. A significant reduction in the number of naive follicular B cells, combined with an impaired ability to convert them into mature memory B cells leaves these aged mice highly vulnerable to new infections. It is likely that the same principle applies to humans. A plausible conclusion is that aggressive vaccination campaigns accelerate the pace at which an individual’s immune system reaches an “aged” status due to exuberant generation of memory B cells in response to the artificial stimuli induced by repeated vaccination.

It has now been confirmed that the S1 component of the spike protein shows up in the blood one day after the first mRNA vaccine and remains detectable for up to a month after vaccination, becoming cleared as IgA and IgG antibodies become available. For immune compromised people, it likely stays in the blood much longer, exposing all the tissues — the spleen, the heart, the brain, the gonads, etc. – to the toxic prion-like spike protein.

Today’s children are by far the most vaccinated generation in the history of humankind. If we decide in the near future to deliver a booster COVID-19 shot to them every year, as seems possible given the current climate of enthusiasm for these vaccines, are we inviting disaster for them in years to come? Will their immune system “age” much faster than that of previous generations, due to the exhaustion of the pool of progenitor B cells by all these vaccines? Will they succumb to Parkinson’s disease or other debilitating prion-based neurodegenerative diseases much sooner and in much greater numbers than previous generations? This is an experiment that I hope we finally decide not to carry out.

Summary
There are many reasons to be wary of the COVID-19 vaccines, which have been rushed to market with grossly inadequate evaluation and aggressively promoted to an uninformed public, with the potential for huge, irreversible, negative consequences. One potential consequence is to exhaust the finite supply of progenitor B cells in the bone marrow early in life, causing an inability to mount new antibodies to infectious agents. An even more worrisome possibility is that these vaccines, both the mRNA vaccines and the DNA vector vaccines, may be a pathway to crippling disease sometime in the future. Through the prion-like action of the spike protein, we will likely see an alarming increase in several major neurodegenerative diseases, including Parkinson’s disease, CKD, ALS and Alzheimer’s, and these diseases will show up with increasing prevalence among younger and younger populations, in years to come. Unfortunately, we won’t know whether the vaccines caused this increase, because there will usually be a long time separation between the vaccination event and the disease diagnosis. Very convenient for the vaccine manufacturers, who stand to make huge profits off of our misfortunes — both from the sale of the vaccines themselves and from the large medical cost of treating all these debilitating diseases.

Stephanie Seneff is a Senior Research Scientist at the MIT Computer Science and Artificial Intelligence Laboratory. She received the B.S. degree in Biophysics in 1968, the M.S. and E.E. degrees in Electrical Engineering in 1980, and the Ph.D degree in Electrical Engineering and Computer Science in 1985, all from MIT. For over three decades, her research interests have always been at the intersection of biology and computation: developing a computational model for the human auditory system, understanding human language so as to develop algorithms and systems for human computer interactions, as well as applying natural language processing (NLP) techniques to gene predictions. She has published over 170 refereed articles on these subjects, and has been invited to give keynote speeches at several international conferences. She has also supervised numerous Master’s and PhD theses at MIT. In 2012, Dr. Seneff was elected Fellow of the International Speech and Communication Association (ISCA).

Originally published on GreenMedInfo.com

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Re: Whoa!!! The Vaxxes and neurodegenerative disease
« Reply #304 on: January 12, 2022, 08:20:58 AM »
Nuremberg 2.0 is coming.



By Natali _ Mis/Shutterstock
By Natali _ Mis/Shutterstock
HEALTH NEWS
SARS-COV-2 Vaccines and Neurodegenerative Disease
By Stephanie Seneff and GreenMedInfo January 11, 2022 Updated: January 11, 2022biggersmaller Print
Since December 2021, when several novel unprecedented vaccines against SARS-CoV-2 began to be approved for emergency use, there has been a worldwide effort to get these vaccines into the arms of as many people as possible as fast as possible. These vaccines have been developed “at warp speed,” given the urgency of the situation with the COVID-19 pandemic. Most governments have embraced the notion that these vaccines are the only path towards resolution of this pandemic, which is crippling the economies of many countries.

Thus far, there are four different vaccines that have been approved for emergency use for protection against COVID-19 in the US and/or Europe. Two (the Moderna vaccine and the Pfizer/BioNTech vaccine) are based on mRNA technology, whereas the other two (produced by Johnson & Johnson and AstraZeneca) are based on a double-stranded DNA recombinant viral vector. The mRNA vaccines contain only the code for the SARS-CoV-2 envelope spike protein, whereas the DNA-based vaccines both contain an adenovirus viral vector that has been augmented with DNA that codes for the SARS-CoV-2 spike protein. The DNA-based vaccines have a certain advantage over the RNA-based vaccines in that they do not have to be stored at deep-freeze temperatures, because double-stranded DNA is much more stable than single-stranded RNA. But a disadvantage is that those who have been exposed to natural forms of the adenovirus have antibodies to the virus that will likely block the synthesis of the spike protein, and therefore not afford protection against SARS-CoV-2.

In this regard, the AstraZeneca (AZ) vaccine has a slight advantage over the Johnson & Johnson (J&J) vaccine because the virus normally infects chimpanzees rather than humans, so fewer people are likely to have been exposed to it. On the other hand, several studies have shown that viruses that normally infect one species can cause tumors if they are injected into a different species. For example, a human adenovirus injected into baboons caused retinoblastoma (cancer of the eye) in the baboons . So, it can’t be ruled out that the AZ vaccine could lead to cancer.

People don’t realize that these vaccines are vastly different from the many childhood vaccines we are now used to getting early in life. I find it shocking that the vaccine developers and the government officials across the globe are wrecklessly pushing these vaccines on an unsuspecting population. Together with Dr. Greg Nigh, I recently published a peer-reviewed paper on the technology behind the mRNA vaccines and the many potentially unknown consequences to health . Such unprecedented vaccines normally take twelve years to develop, with only a 2% success rate, but these vaccines were developed and brought to market in less than a year. As a consequence, we have no direct knowledge of any effects that the vaccines might have on our health over the long term. However, knowledge about how these vaccines work, how the immune system works and how neurodegenerative diseases come about can be brought to bear on the problem in order to predict potential devastating future consequences of the vaccines.

The mRNA in these vaccines codes for the spike protein normally synthesized by the SARS-CoV-2 virus. However, both the mRNA and the protein it produces have been changed from the original version in the virus with the intent to increase rate of production of the protein in an infected cell and the durability of both the mRNA and the spike protein it codes for. Additional ingredients like cationic lipids and polyethylene glycol are also toxic with unknown consequences. The vaccines were approved for emergency use based on grossly inadequate studies to evaluate safety and effectiveness.

Our paper showed that there are several mechanisms by which these vaccines could lead to severe disease, including autoimmune disease, neurodegenerative diseases, vascular disorders (hemorrhaging and blood clots) and possibly reproductive issues. There is also the risk that the vaccines will accelerate the emergence of new strains of the virus that are no longer sensitive to the antibodies produced by the vaccines. When people are immune compromised (e.g., taking chemotherapy for cancer), the antibodies they produce may not be able to keep the virus in check because the immune system is too impaired. Just as in the case of antibiotic resistance, new strains evolve within an infected immune-compromised person’s body that produce a version of the spike protein that no longer binds with the acquired antibodies. These new strains quickly come to dominate over the original strain, especially when the general population is heavily vaccinated with a vaccine that is specific to the original strain. This problem is likely going to necessitate the repeated rollout of new versions of the vaccine at periodic intervals that people will have to receive to induce yet another round of antibody production in an endless game of cat and mouse.

Like the mRNA vaccines, the DNA vaccines are based on novel biotech gene editing techniques that are brand new, so they too are a massive experiment unleashed on a huge unsuspecting population, with unknown consequences. Both DNA vector vaccines have been associated with a very rare condition called thrombocytopenia, in which platelet counts drop precipitously, resulting in system-wide blood clots and a high risk of cerebral hemorrhaging [5]. This is likely due to an autoimmune reaction to the platelets, and it comes with a high risk of mortality. In the case of the AZ vaccine, this has caused over 20 European countries to temporarily pause their vaccination programs [6]. And the United States called a temporary halt on the J&J vaccine.

Even experts don’t really understand the mechanism as of now, although a fascinating theory to explain this depends on the fact that DNA vector vaccines require the DNA to be copied into RNA in the nucleus, and this presents the possibility of producing an incomplete copy, generated through “splice variants,” that is missing the code for attaching to the membrane. These soluble partial sequences wander off to other parts of the body and bind to ACE2 receptors throughout the vasculature. Antibodies to these ACE2-bound partial spike fragments cause an acute inflammatory response that results in disseminated intravascular coagulation (DIC).

How to Make an Adenovirus DNA Vector Vaccine
The adenovirus vaccines are created through techniques that the average citizen can’t possibly fathom could even exist. For the AZ vaccine, the bulk of the DNA in the vaccine codes for the various proteins that are needed by a strain of adenovirus that mainly infects chimpanzees and causes cold-like symptoms. However, it is not a “normal” version of this cold virus. First of all, it has been stripped of certain genes that it needs in order to replicate, and for this reason it is referred to as an “adenovirus vector.” This defect, it is argued, keeps it from actually infecting the vaccinated patient. Secondly, it is modified, through gene editing techniques, to create a recombinant version of the virus that contains the complete coding sequence for the SARS-CoV-2 spike protein, spliced into its DNA sequence – the same protein that the RNA vaccines code for. The recombinant DNA is a linear double-stranded DNA sequence where proteins from two different species are integrated through gene editing.

Since this virus can’t proliferate, it is difficult to manufacture large quantities of it. But they solved this problem by making use of a genetically modified version of a human cell line, called HEK (human embryonic kidney) 293 cells, where the human cell’s DNA was transfected long ago with fragments of the genome of an adenovirus – conveniently providing the defective recombinant virus with the missing proteins it needs to be able to proliferate. Within a culture of these HEK 293 cells, the virus can replicate, assisted by the proteins that are produced by the host cells. The HEK 293 cells originally came from a kidney of an aborted fetus, and it has been maintained in culture ever since the 1970s, because it was modified to become immortal, with the help of the adenovirus. Although it was obtained from a kidney, it is not a kidney cell. In fact, it has many properties that are characteristic of a neuronal stem cell. The fact is, they don’t really know what kind of cell it is. The ability of a cell line to survive indefinitely is a feature of tumor cells. Although the vaccine is “purified” during the processing, there is no guarantee that it is not contaminated with remnants from the host cells, i.e., human DNA of a neuronal tumor cell line. It does not seem like a good idea to inject the DNA of a human tumor cell into anyone.

The J&J vaccine has a very similar manufacturing process, except with a different adenovirus strain and a different human host cell. For J&J, the host cell is another fetal cell line harvested long ago and made immortal through the incorporation of adenovirus genes into the host human genome. This cell line was taken from the retina of the eye of the fetus.

The Spike Protein is Toxic
The COVID-19 vaccines are all based on supplying genetic code to produce the spike protein that is the main constituent of the SARS-CoV-2 protein cage that encloses its RNA contents. Both the DNA vector and the RNA vaccines induce the vaccine-infected cell to manufacture many copies of the spike protein according to the code. Through experimentation, researchers have determined that the spike protein is toxic even when introduced all by itself. In a revealing experiment, researchers injected spike protein into hamsters, and found that it was taken up by endothelial cells lining the blood vessels, via ACE2 receptors. This caused a downregulation of ACE2, which had significant effects on the metabolic policy in the cells. In particular, it inhibited the synthesis of mitochondria, and caused the existing mitochondria to fragment. Mitochondria are the organelles in the cell that produce large quantities of ATP (the energy currency of cells) by oxidizing nutrients, while consuming oxygen and producing water and carbon dioxide. The spike protein reduced the production of ATP by mitochondria and increased glycolysis — the alternative, much less efficient, way to produce ATP without using oxygen. This metabolic change towards getting energy through glycolysis is a characteristic feature of cancer cells and of neurons in neurodegenerative diseases such as Alzheimer’s.

In another experiment, researchers showed that spike protein can cross the blood-brain barrier in mice and be taken up by neurons throughout the brain. This too is likely mediated by ACE2 receptors (which neurons also produce). These same researchers also showed that spike protein administered in the nose was able to reach the brain by traveling along the olfactory nerve. When they induced inflammation in the brain through exposure to lipopolysaccharide (LPS), they saw an increased uptake of spike protein into the brain, which they hypothesized was caused by increased leakiness in the barrier. As you will see, these points become important when we later consider what happens following a SARS-CoV-2 vaccine, which is designed to induce inflammation.

Many people suffering from COVID-19 have experienced symptoms characteristic of the central nervous system such as headache, nausea, dizziness, fatal brain blood clots and encephalitis. In an advanced 3D microfluid model of the human BBB, researchers in the United States showed that the spike protein by itself disrupts the blood brain barrier by inducing an inflammatory state, and they proposed that this could be the source of such symptoms.

A published preprint found widespread expression of ACE2 in many parts of the brain. ACE2 was expressed in astrocytes, pericytes (cells that wrap around the endothelial cells lining capillary walls) and in endothelial cells — and all of these are key components of the blood-brain barrier. Perhaps of even greater concern is that ACE2 was highly expressed in the substantia nigra, a brain-stem nucleus where damaged dopaminergic neurons lead to Parkinson’s disease.

Bell’s Palsy, Autism and Parkinson’s Disease
In a paper aptly titled, “Is COVID-19 a Perfect Storm for Parkinson’s Disease?” researchers made a strong case for the possibility that we will see an increase in Parkinson’s disease in the future, due to the COVID-19 pandemic. They refer to three separate cases where acute Parkinsonism developed shortly after a COVID-19 infection. They proposed that systemic inflammation caused by severe COVID-19 could trigger neuroinflammation in the substantia nigra, killing off dopaminergic neurons. These neurons express high levels of the ACE2 receptor, making them highly vulnerable to the spike protein. A viral infection is known to upregulate α-synuclein, which, in high concentrations, forms soluble oligomers that then precipitate out as fibrils and accumulate within “Lewy bodies” that are tightly linked to Parkinson’s disease. Further corroboration of this idea comes from a paper which demonstrated that an infection with SARS-CoV-2 causes brain inflammation in macaques and induces the formation of Lewy bodies.

Parkinson’s disease is the second most common neurodegenerative disorder and the most common neurodegenerative motor disorder. The root cause of nearly 90% of cases remains unknown, but it has been theorized that viral infections are often involved. It can be argued that the loss of a sense of smell and/or taste in association with COVID-19 is a sign of a Parkinsonian link, since this symptom is also an early sign of Parkinson’s disease.

The mRNA vaccines appear to disrupt the body’s ability to keep latent viruses from “waking up” and causing disease symptoms. This observation is based on the fact that shingles and facial palsy (Bell’s palsy) are being commonly reported in side-effect reports in the FDA’s Vaccine Adverse Event Reporting System. As of May 21, 2021, over 2500 reports of Bell’s palsy following COVID-19 vaccines had appeared in VAERS. A primary cause of Bell’s palsy is the activation of latent viral infections, most notably Herpes simplex and Varicella zoster, Varicella zoster is also the virus responsible for shingles.

While Bell’s palsy usually resolves over time, there can be some serious longer-term consequences. Pregnant women who are diagnosed with active herpes infections during pregnancy have a 2-fold increased risk of having an autistic male child from that pregnancy. This should make a pregnant woman hesitate to get a SARS-CoV-2 vaccine. Bell’s palsy can also be a risk factor for Parkinson’s disease much later in life. A study on nearly 200 Parkinson’s disease patients compared with age- and gender-matched controls found that six of the Parkinson’s patients had had an earlier diagnosis of Bell’s palsy, whereas none of the control patients had. There’s also a link between autism and Parkinson’s disease. A study on autistic adults over 39 years old found that one third of them had symptoms that meet the criteria for a Parkinson’s diagnosis.

Prion Diseases
Prion diseases are a group of severe neurodegenerative diseases that are caused by misfolded prion proteins. The most common prion disease in humans is the always-fatal sporadic Creutzfeldt-Jakob disease (CJD), which accounts for more than 85% of the cases. Prion diseases are more specifically called transmissible spongiform encephalopathies (TSEs), and infection can spread through exposure to misfolded proteins as “infective” agents, without requiring a live pathogen. PrP is the name given to the specific prion protein associated with these TSEs. Misfolded PrP proteins act as a seed or catalyst that then recruits other molecules of PrP to misfold in the same way and glom together into pathogenic fibrils.

MADCOW, the disease that affected a large number of cows in Europe beginning in the 1990s, is probably the best-known TSE. While eating beef from an infected animal is a very rare risk factor, most cases of Creutzfeldt-Jakob disease occur for unknown reasons, and no other risk factors have been identified. A study based in Switzerland confirmed that many patients who died of Creutzfeldt-Jakob disease had detectable levels of a prion protein in their spleen and muscles, in addition to the olfactory lobe and the central nervous system. More generally, diseases involving misfolded PrPs have consistently been found to involve an initial early phase of prion replication in the spleen which happens long before overt symptoms appear. This point becomes important when we consider whether the COVID-19 vaccines might cause prion diseases.

PrP has a unique feature that it contains multiple copies of a characteristic motif in its amino acid sequence that is called a “GxxxG” motif, also known as a “glycine zipper”. These proteins normally fold into a characteristic shape called an alpha helix, which allows the protein to penetrate the plasma membrane. The glycines in the zipper motif play an essential role in cross-linking and stabilizing alpha helices. This glycine zipper motif is also a common characteristic of many transmembrane proteins (proteins that cross the membrane of the cell).

Indeed, the coronavirus spike protein has a GxxxG motif in its transmembrane domain (specifically, GFIAG — glycine, phenylalanine, isoproline, alanine, glycine). There is a platform called “Uniprot” where you can look up the sequence of specific proteins. The Uniprot entry for the SARS-CoV-2 spike protein has five glycine zipper sequences altogether. According to J. Bart Classen, the SARS-CoV-2 spike protein has the ability “to form amyloid and toxic aggregates that can act as seeds to aggregate many of the misfolded brain proteins and can ultimately lead to neurodegeneration.”

Many neurodegenerative diseases have been linked to specific proteins that have prion-like properties, and these diseases are characterized as protein-misfolding diseases or proteopathies. Like PrP, prion-like proteins become pathogenic when their alpha helices misfold as beta sheets, and the protein is then impaired in its ability to enter the membrane. These diseases include Alzheimer’s, amyotrophic lateral sclerosis (ALS), Huntington’s disease and Parkinson’s disease, and each of these is associated with a particular protein that misfolds and accumulates in inclusion bodies in association with the disease. We already saw that Parkinson’s disease is characterized by Lewy bodies in the substantia nigra that accumulate misfolded α-synuclein.

Glycines within the glycine zipper transmembrane motifs in the amyloid beta precursor protein (APP) play a central role in the misfolding of amyloid beta linked to Alzheimer’s disease (Decock et al., 2016). APP contains a total of four GxxxG motifs (one fewer than the spike protein).

A case study presented the case of a man who developed CKD simultaneously with symptomatic COVID-19. The authors proposed that infection with SARS-CoV-2 precipitates or accelerates neurodegenerative diseases. A theoretical paper published by researchers in India showed that the spike protein binds to a number of aggregation-prone prion-like proteins, including amyloid beta, α-synuclein, tau, PrP and TDP-43. They argued that this could initiate aggregation of these proteins in the brain, leading to neurodegeneration.

Tracing the Vaccine Trail to the Spleen
It is important to understand what happens to the contents of a vaccine after it is injected into the arm. Where does it travel in the body, and what does it do in the places where it settles in?

Vaccine developers are keen to know whether the vaccine induces a strong immune response, reflected in high antibody production against the spike protein, in the case of COVID-19 vaccines. And to do this, they need to trace its movement in the body.

CD8+ T-cells are cytotoxic immune cells that can kill cells that are infected with a virus. They detect an immune complex with viral proteins that are exposed on the surface of an infected cell. A study on an adenovirus-vector based vaccination of mice used clever methods to produce a marker that could track the activity of CD8+ T-cells in the lymph system and the spleen, in the days following vaccination. It can be inferred that immune cells (antigen-presenting cells, where the “antigen” is the spike protein) were initially present at the arm muscle injection site and synthesized the virus spike protein from the vaccine DNA code, exposing it on their surface. Once activated by the foreign protein, they translocated into the draining lymph nodes and finally made their way to the spleen via the lymph system. The CD8+ T-cells are idly waiting within the lymphatics until they spot an infected immune cell. Researchers could detect activation of CD8+ immune cells over time and inferred that this was caused by the arrival of the contents of the vaccine to the site where these immune cells reside. Activated CD8+ T-cells first appeared in the draining lymph nodes, but after five days began to show up in the spleen. Their numbers there peaked sharply by 12 days and then remained high with a slow decay up to 47 days, when the researchers stopped looking. What this means is that the vaccine is picked up by antigen-presenting cells at the injection site and carried to the spleen via the lymph system. The carrier cells then hang out in the spleen for a long time. And this is where the danger lies in terms of the potential to cause prion disease.

In the paper that Greg Nigh and I published recently on the mRNA vaccines, we argued that the mRNA vaccines are rather perfectly set up to produce a very dangerous situation in the spleen that is poised to launch a prion disease. Given the fact that the DNA vector vaccines also end up concentrated in the spleen, I think that the same thing holds true for them as well. The spleen is where the action is for seeding misfolded prion proteins. The vaccine-infected cells have been programmed to produce large amounts of spike proteins. Prion proteins misfold into damaging beta-sheet oligomers when there are too many of them in the cytoplasm. Might the spike protein do the same?

Three out of the four COVID-19 vaccines currently on the market in the U.S. and Europe (Pfizer, Moderna, and J&J) use a genetic code for the spike protein that has been slightly tweaked, in order to produce a more potent antibody response. Normally, after binding to the ACE2 receptor, the spike protein spontaneously changes its shape in a dramatic way in order to fuse with the membrane of the cell. In a Web publication, Ryan Cross described this action very graphically based on a spring-like model, as follows: “When the spike protein binds to a human cell, that spring is released, and the two helices and the loop straighten into one long helix that harpoons the human cell and pulls the virus and human membranes close together until they fuse.” As Cross explains, through trial and error, but taking structural information into account, researchers came up with the idea of swapping out two adjacent amino acids for prolines in the membrane fusion domain in order to stabilize the shape of the spike protein in its pre-fusion form. In this form, it exposes critical antigenic areas, and this assures more rapid formation of matching antibodies, the only goal of the vaccine design. This also prevents the protein from fusing with the plasma membrane of a host cell. I’d imagine that the spike protein attaches to the ACE2 receptor and then gets stuck there, like a sitting duck. But a worrisome thought is whether this open state, not fused with the membrane, might more closely resemble the shape of a misfolded prion-like protein like amyloid beta than does the collapsed shape it needs to go into the membrane?

Tetz and Tetz have argued in a published online preprint that prion-like domains in the spike protein enable higher affinity for the ACE2 receptor, making the virus more virulent than its earlier cousins. These same authors published an earlier peer-reviewed journal paper where they observed that many other viruses have proteins in their coat that have distinct features of prion proteins.

Germinal Centers and Parkinson’s Disease
Germinal centers in the spleen are a primary factory where antibodies against specific antigens (such as the spike protein) are manufactured and perfected. Makers of the mRNA vaccines were pleased to see that antigen-presenting cells (mainly dendritic cells), originally attracted to the site of the injection, take up the mRNA particles and then migrate via the lymph system to the spleen in high numbers and induce high levels of antibody production in these germinal centers.

Unfortunately, these same germinal centers are a primary site for the initiation of a process of producing and distributing misfolded prion proteins, often seeded by viral proteins, and triggered by an acute inflammatory response.

B cells, also known as B lymphocytes, are a type of immune cell that is the key player in the process that leads to the production of specific antibodies to a foreign antigen [38]. They originate from precursor cells in the bone marrow, and then migrate to the spleen and other lymphoid organs, where they bind to antigens presented to them by antigen-presenting cells, such as the dendritic cells. A maturation process beginning with a multipotent progenitor B cell ends with a mature “memory” B cell that has gone through a complex process to perfect its antibody production process to specifically match the antigen it has been assigned to (e.g., the spike protein). B cells also go through another process called class switching, which changes the type of antibody they produce from one class to another, without changing its specificity to the antigen.

Antibodies are also known as immunoglobulins (Igs), and the possible classes include IgM, IgG, IgA and IgE. IgM is the first immunoglobulin class that is produced (primarily in the spleen), and it is converted into IgG through class switching. IgG is the dominant class in the blood, making up 75% of the serum antibodies, and it is essential for clearing infections in the tissues. Long-lived mature memory B cells cruise the blood stream looking for any appearances of the antigen they have been assigned to, but they are useless for anything else. When the virus they’ve been trained to match mutates to the point where their antibodies no longer match well, they become useless even for the disease they’re trained to fight.

When mice are injected with PrP in the abdomen (intraperitoneal injection), the PrP shows up very quickly in the spleen. From there, the PrP travels along the spinal cord and the vagus nerve to reach the brain, causing prion disease [39]. As we will soon see, α-synuclein, the prion-like protein linked to Parkinson’s disease, also makes its way to the brain from the spleen along the vagus nerve. The mRNA vaccines set up perfect conditions in the spleen for the formation and distribution of conglomerates made up of misfolded α-synuclein, PrP and spike protein.

While α-synuclein causes neurodegenerative disease when it misfolds, in its normal shape it is an active participant in the immune response. α-Synuclein facilitates the processes that lead to antibody production in response to foreign antigens. Dendritic cells express α-synuclein, and it is upregulated (over-expressed) in response to stressors, such as the mRNA, the cationic lipids, and the PEG in the mRNA vaccines. Much can be learned by studying mice that have been genetically engineered to have a defective version of α-synuclein. These mice have a decreased capacity to clear pathogens through phagocytosis, and an impairment in the ability to generate B cells from precursor stem cells. They also had a four-fold reduction in progenitor B cells in the bone marrow. The amount of immunoglobulin G was reduced compared to wildtype, suggesting impaired class switching. Altogether, they are unable to mount an effective immune response to antigens, whether they come from a natural threat or a vaccine.

Dendritic cells under stress accumulate prion proteins and release them into small lipid particles called exosomes, which are then distributed throughout the body, either along nerve fibers or in the general circulation. There is reason to believe that these vaccines will accelerate the release of exosomes containing misfolded prion-like spike proteins that are being produced in large amounts under instruction from the vaccines. These spike proteins will act as seeds to cause α-synuclein and PrP to also misfold and form toxic oligomers together with the spike protein, which are released into the extracellular space as exosomes. These exosomes, released under the severe stress conditions induced by the vaccine, then carry prion proteins into the brain along the vagus nerve, to initiate prion diseases.

Impaired Immune Response due to Over-vaccination
A characteristic of the elderly is an impaired ability to mount antibodies against new pathogenic threats, and this is reflected in a failure to generate protective antibodies in response to vaccination. It has been demonstrated in experiments with mice that aged mice have an overabundance of long-lived memory (antigen-experienced) B cells, and this is paired with an inability to generate new B cells from progenitor cells in the bone marrow, as well as impairment in the process of refinement of the antibody response in germinal centers in the spleen and the associated class switching that produces effective IgG antibodies. A significant reduction in the number of naive follicular B cells, combined with an impaired ability to convert them into mature memory B cells leaves these aged mice highly vulnerable to new infections. It is likely that the same principle applies to humans. A plausible conclusion is that aggressive vaccination campaigns accelerate the pace at which an individual’s immune system reaches an “aged” status due to exuberant generation of memory B cells in response to the artificial stimuli induced by repeated vaccination.

It has now been confirmed that the S1 component of the spike protein shows up in the blood one day after the first mRNA vaccine and remains detectable for up to a month after vaccination, becoming cleared as IgA and IgG antibodies become available. For immune compromised people, it likely stays in the blood much longer, exposing all the tissues — the spleen, the heart, the brain, the gonads, etc. – to the toxic prion-like spike protein.

Today’s children are by far the most vaccinated generation in the history of humankind. If we decide in the near future to deliver a booster COVID-19 shot to them every year, as seems possible given the current climate of enthusiasm for these vaccines, are we inviting disaster for them in years to come? Will their immune system “age” much faster than that of previous generations, due to the exhaustion of the pool of progenitor B cells by all these vaccines? Will they succumb to Parkinson’s disease or other debilitating prion-based neurodegenerative diseases much sooner and in much greater numbers than previous generations? This is an experiment that I hope we finally decide not to carry out.

Summary
There are many reasons to be wary of the COVID-19 vaccines, which have been rushed to market with grossly inadequate evaluation and aggressively promoted to an uninformed public, with the potential for huge, irreversible, negative consequences. One potential consequence is to exhaust the finite supply of progenitor B cells in the bone marrow early in life, causing an inability to mount new antibodies to infectious agents. An even more worrisome possibility is that these vaccines, both the mRNA vaccines and the DNA vector vaccines, may be a pathway to crippling disease sometime in the future. Through the prion-like action of the spike protein, we will likely see an alarming increase in several major neurodegenerative diseases, including Parkinson’s disease, CKD, ALS and Alzheimer’s, and these diseases will show up with increasing prevalence among younger and younger populations, in years to come. Unfortunately, we won’t know whether the vaccines caused this increase, because there will usually be a long time separation between the vaccination event and the disease diagnosis. Very convenient for the vaccine manufacturers, who stand to make huge profits off of our misfortunes — both from the sale of the vaccines themselves and from the large medical cost of treating all these debilitating diseases.

Stephanie Seneff is a Senior Research Scientist at the MIT Computer Science and Artificial Intelligence Laboratory. She received the B.S. degree in Biophysics in 1968, the M.S. and E.E. degrees in Electrical Engineering in 1980, and the Ph.D degree in Electrical Engineering and Computer Science in 1985, all from MIT. For over three decades, her research interests have always been at the intersection of biology and computation: developing a computational model for the human auditory system, understanding human language so as to develop algorithms and systems for human computer interactions, as well as applying natural language processing (NLP) techniques to gene predictions. She has published over 170 refereed articles on these subjects, and has been invited to give keynote speeches at several international conferences. She has also supervised numerous Master’s and PhD theses at MIT. In 2012, Dr. Seneff was elected Fellow of the International Speech and Communication Association (ISCA).

Originally published on GreenMedInfo.com

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WSJ: Where's the therapeutics?
« Reply #307 on: January 12, 2022, 07:40:35 PM »
Biden’s Operation Snail Speed on Covid Therapies
Less than 1% of $1.9 trillion in last March’s relief cash went for treatments.
By The Editorial Board
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Jan. 12, 2022 6:32 pm ET
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The GlaxoSmithKline headquarters in London.
PHOTO: MATTHEW CHILDS/REUTERS

The Biden Administration on Tuesday ordered another 600,000 doses of GlaxoSmithKline and Vir Biotechnology’s monoclonal antibody. Last week it increased its order of Pfizer’s antiviral Paxlovid by 10 million. Great, but these treatments will probably arrive after the Omicron Covid variant crests. Why didn’t it order more treatments sooner?

That’s an especially good question given that the stated purpose of Democrats’ $1.9 trillion spending bill last March was Covid relief. Yet less than 1% of the spending was allocated for therapies. About as much money was given last year to New York’s financially ailing transit system as the Administration spent procuring Covid therapies. The result: A persistent treatment shortage and countless preventable deaths.

***
It was obvious even early in the pandemic that treatments were going to be critical to living with Covid, especially oral antivirals that patients can pick up at pharmacies soon after developing symptoms. Francis Collins, then the National Institutes of Health director, explained this on CBS’s “60 Minutes” in March. But therapies were a very low priority for the White House Covid team.

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In June 2021 the Administration placed an advance order for 1.7 million courses of Merck and Ridgeback Biotherapeutics’ antiviral molnupiravir, which had shown promise in early trials. In November after stronger data came out, it increased the order to 3.1 million courses, which were to be delivered by early 2022. Why not more?

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Perhaps because the White House believed money would be better spent on monoclonal antibodies and Pfizer’s Paxlovid, which were shown to be somewhat more effective in trials. But the Administration didn’t order nearly enough of those either.

Monoclonals in short supply had to be rationed during the summer Delta surge. In mid-September, as Delta was receding, the Administration ordered 1.4 million doses of Regeneron’s monoclonal and 388,000 of Eli Lilly’s . Unable to get enough from the feds for his state, Florida Gov. Ron DeSantis in September went around the Administration to purchase the monoclonal from GSK and Vir.


Their monoclonal was authorized by the Food and Drug Administration in May. It is unique in neutralizing both the SARS virus and Covid-19, making it less susceptible to new variants. It holds up well against Omicron while those by Regeneron and Lilly haven’t. But the Administration apparently didn’t think GSK-Vir’s was needed.

In June GSK had 450,000 doses on hand. Yet the Administration waited until the fall to order $1 billion in treatments, covering about 450,000 doses. On Nov. 18, the Administration also ordered 10 million courses of Pfizer’s Paxlovid after trial data showed it reduced hospitalizations by nearly 90%. Yet manufacturing the pills takes six to eight months so supply has been very limited.

Had the Administration ordered more treatments sooner, more would have been available this winter. The Trump Administration’s Operation Warp Speed accelerated vaccine development and production by placing advance orders so a supply would be available as soon as the FDA approved a vaccine. President Biden could have done the same for treatments but didn’t.

Instead, the Administration has focused relentlessly on masking, testing and vaccines with therapies as a fourth priority. The focus has been on preventing infection, rather than treating it. Vaccines prevent serious disease. But as we are learning with Omicron, they don’t stop infection or transmission. Despite President Biden’s efforts at coercion, many Americans remain unvaccinated.

Masking seems increasingly beside the point with Omicron spreading like wildfire and millions of Americans wearing them improperly. Testing can help people who want to protect the vulnerable in their orbit, but the Administration also failed to prepare for a winter surge in testing demand.

***
Health and Human Services Secretary Xavier Becerra oversees therapy procurement, but he’s been missing in action. He didn’t even appear at a Senate hearing Tuesday with officials Anthony Fauci, Janet Woodcock and Rochelle Walensky. Then again, he has no health-care expertise and his only apparent credential for the job was suing the Trump Administration as California Attorney General.

As Omicron spreads far and wide, Americans are beginning to appreciate that we all may eventually be infected. President Biden’s campaign promise to “shut down the virus” was always a false boast and will never be met. Fortunately, Omicron is so far causing milder illness. But living with endemic Covid means that therapies are crucial.

Having more therapies this winter would have reduced the burden on hospitals and might have saved thousands of lives.

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Re: WSJ: Biden’s Operation Snail Speed on Covid Therapies
« Reply #308 on: January 13, 2022, 06:48:26 AM »
I like the term for the Biden administration on anything good we wish they would do, "Operation Snailspeed".

Harris' border task force = Operation Snailspeed?

He wasn't Snailspeed closing pipelines and energy supply.
« Last Edit: January 13, 2022, 06:52:48 AM by DougMacG »

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Re: WSJ: Biden’s Operation Snail Speed on Covid Therapies
« Reply #309 on: January 13, 2022, 06:55:50 AM »
I like the term for the Biden administration on anything good we wish they would do, "Operation Snailspeed".

Harris' border task force = Operation Snailspeed?

He wasn't Snailspeed closing pipelines and energy supply.

Operation Cloward-Piven.



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The Situation in Italy
« Reply #315 on: January 17, 2022, 12:40:14 PM »
Sent to me by someone who follows my FB page.  It is in Italian, but English subtitles are an option:

https://www.youtube.com/watch?v=cE-T8VnymJA



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Better than you!
« Reply #318 on: January 17, 2022, 01:18:27 PM »




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Mercola: Children and the Vaxx
« Reply #325 on: January 18, 2022, 03:47:39 AM »
Joseph Mercola: Do More Children Die From the COVID Shot Than From COVID? (theepochtimes.com)

 
January 15, 2022 Updated: January 16, 2022

According to published research, children are at risk for potentially lifelong health effects from the jab. Read here to learn what the experts say.

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The video above features Collette Martin, a practicing nurse who testified before a Louisiana Health and Welfare Committee hearing December 6, 2021. Martin claims she and her colleagues have witnessed “terrifying” reactions to the COVID shots among children—including blood clots, heart attacks, encephalopathy and arrhythmias—yet their concerns are simply dismissed.



Among elderly patients, she’s noticed an uptick in falls and acute onset of confusion “without any known ideology.” Coworkers are also experiencing side effects, such as vision and cardiovascular problems.



Martin points out that few doctors or nurses are aware the U.S. Vaccine Adverse Events Reporting System (VAERS) even exists, so injury reports are not being filed. Hospitals also are not gathering data on COVID jab injuries in any other ways, so there’s no data to investigate even if you wanted to. According to Martin:

“We are not just seeing severe acute [short term] reactions with this vaccine, but we have zero idea what any long-term reactions are. Cancers, autoimmune [disorders], infertility. We just don’t know.

We are potentially sacrificing our children for fear of MAYBE dying, getting sick of a virus — a virus with a 99% survival rate. As of now, we have more children that died from the COVID vaccine than COVID itself.

And then, for the Health Department to come out and say the new variant [Omicron] has all the side effects of the vaccine reactions we’re currently seeing — it’s maddening, and I don’t understand why more people don’t see it. I think they do, but they fear speaking out and, even worse, being fired … Which side of history will you be on? I have to know that this madness will stop.”

What the VAERS Data Tell Us About COVID Jab Risks

I recently interviewed Jessica Rose, Ph.D., a research fellow at the Institute for Pure and Applied Knowledge in Israel, about what the VAERS data tell us about the COVID jabs’ risks. As noted by Rose, the average number of adverse event reports following vaccination for the past 10 years has been about 39,000 annually, with an average of 155 deaths. That’s for all available vaccines combined.



The COVID jabs alone now account for 983,756 adverse event reports as of December 17, 2021, including 20,622 deaths—and this doesn’t include the underreporting factor, which we know is significant and likely ranges from five to 40 times higher than reported. Most doctors and nurses don’t even know what VAERS is and even if they do, they chose not to report the incidents.



In the case of the COVID jabs, 50 percent of the deaths occur within 48 hours of injection. It’s simply not conceivable that 10,000 people died two days after their shot from something other than the shot. It cannot all be coincidence. Especially since so many of them are younger, with no underlying lethal conditions that threaten to take them out on any given day. A full 80 percent have died within one week of their jab, which is still incredibly close in terms of temporality.



Children Risk Permanent Heart Damage

Aside from the immediate risk of death, children are also at risk for potentially lifelong health problems from the jab. Myocarditis (heart inflammation) has emerged as one of the most common problems, especially among boys and young men.



In early September 2021, Tracy Beth Hoeg and colleagues posted an analysis of VAERS data on the preprint server medRxiv, showing that more than 86 percent of the children aged 12 to 17 who report symptoms of myocarditis were severe enough to require hospitalization.



Cases of myocarditis explode after the second shot, Hoeg found, and disproportionally affect boys. A full 90 percent of post-jab myocarditis reports are males, and 85 percent of reports occurred after the second dose. According to Hoeg et al.:

“The estimated incidence of CAEs [cardiac adverse events] among boys aged 12-15 years following the second dose was 162 per million; the incidence among boys aged 16-17 years was 94 per million. The estimated incidence of CAEs among girls was 13 per million in both age groups.”

No doubt, doctors are seeing an increase in myocarditis, but few are willing to talk about it. In a recent Substack post, Steve Kirsch writes:

“I just read a comment on my private ‘healthcare providers only’ substack. An estimated100X elevation in rate of myocarditis, but nobody will learn of it since cardiologists aren’t going to speak out for fear of retribution.



His comment was a private conversation he had with a pediatric cardiologist. The cardiologist is never going to say this in public, to the press, or have his name revealed since his first duty is to his family (keeping his job).



If a ‘fact checker’ called the cardiologist, he might either refuse to comment or say ‘I’m seeing somewhat more cases after the vaccine rolled out.’ Here’s the exact comment that was posted to the private substack:



‘Pre-jab, one or two cases per year of myocarditis. Now, half his waiting room. Tells parents they are ‘studying’ the causality. Refers them to infectious disease specialist for discussions on their other children.



Admits he and about 50% of his colleagues know what’s going on but are too terrified to speak out for fear of retaliation from hospitals and state licensing boards.



Other 50% don’t want to know, don’t care and/or are reveling in the cognitive dissonance (like Dr. Harvey [Cohen] at Stanford) and/or letting loose their authoritarian demon. Good luck with these former colleagues of mine. The stench is overpowering.’



… From 1 or 2 cases per year to ‘half his waiting room.’ I don’t know the size of his waiting room, but it’s at least two people since he said ‘half.’ So, the rate has increased by: 250 day per year open/1.5 avg cases per year=166X.”

Myocarditis Is Not a Mild, Inconsequential Side Effect

Together with Dr. Peter McCullough, in October 2021 Rose also submitted a paper on myocarditis cases in VAERS following the COVID jabs to the journal Current Problems in Cardiology. Everything was set for publication when, suddenly, the journal changed its mind and took it down.



You can still find the pre-proof on Rose’s website, though. The data clearly show that myocarditis is inversely correlated to age, so the risk gets higher the younger you are. The risk is also dose-dependent, with boys having a sixfold greater risk of myocarditis following the second dose.

While our health authorities are shrugging off this risk saying cases are “mild,” that’s a frightening lie. The damage to the heart is typically permanent.



Omicron Poses No Risk to Young People

As noted in a recent analysis by Dr. Robert Malone, (who recently got banned from Twitter but can be found on Substack), the risk-benefit ratio of the COVID shot is becoming even more inverted with the emergence of Omicron, as this variant produces far milder illness than previous variants, putting children at even lower risk of hospitalization or death from infection than they were before, and their risk was already negligible.



Malone is currently spearheading the second Physicians Declaration by the International Alliance of Physicians and Medical Scientists, which has been signed by more than 16,000 doctors and scientists, stating that “healthy children shall not be subjected to forced vaccination” as their clinical risk from SARS-CoV-2 infection is negligible and long term safety of the shots cannot be determined prior to such policies being enacted.



Not only are children at high risk for severe adverse events from the shots, but having healthy, unvaccinated children in the population is crucial to achieving herd immunity.



Shots Double Risk of Acute Coronary Syndrome

Researchers have also found Pfizer and Moderna mRNA COVID-19 shots dramatically increase biomarkers associated with thrombosis, cardiomyopathy and other vascular events following injection.



People who had received two doses of the mRNA jab more than doubled their five-year risk of acute coronary syndrome (ACS), the researchers found, driving it from an average of 11 percent to 25 percent. ACS is an umbrella term that includes not only heart attacks, but also a range of other conditions involving abruptly reduced blood flow to your heart. In a November 21, 2021, tweet, cardiologist Dr. Aseem Malhotra wrote:

“Extraordinary, disturbing, upsetting. We now have evidence of a plausible biological mechanism of how mRNA vaccine may be contributing to increased cardiac events. The abstract is published in the highest impact cardiology journal so we must take these findings very seriously.”

What Do the VAERS Data Show?

Research published in 2017 calculated the background rate of myocarditis in children and youth, showing it occurs at a rate of four cases per million per year. According to the U.S. Census Bureau, as of 2020 there were 73.1 million people under the age of 18 in the U.S. That means the background rate for myocarditis in adolescents (18 and younger) would be about 292 cases per year.



As of December 17, 2021, looking only at U.S. reports and excluding the international ones, VAERS had received:

308 cases of myocarditis among 18-year-olds
252 cases among 17-year-olds
226 cases in 16-year-olds
256 cases in 15-year-olds
193 in 14-year-olds
132 in 13-year-olds
108 in 12-year-olds
In total, that’s 1,475 cases of myocarditis in teens aged 18 and younger—five times the background rate. And again, this does not take into account the underreporting rate, which has been calculated to be anywhere from five to 40.



Meanwhile, the CDC claims that, between March 2020 and January 2021, “the risk for myocarditis was 0.146% among patients diagnosed with COVID-19,” compared to a background rate of 0.009 percent among patients who did not have a diagnosis of COVID-19.



After adjusting for “patient and hospital characteristics,” COVID-19 patients between the ages of 16 and 39 were on average seven times more likely to develop myocarditis than those without COVID.



That said, the CDC stressed that “Overall, myocarditis was uncommon” among all patients, COVID or not. What’s more, only 23.7 percent of myocarditis patients between the ages of 16 and 24 had a history of COVID-19, so a majority of the cases in that age group were not due to COVID.

We’re also not talking about big numbers in terms of actual COVID infections. The weekly adolescent hospitalization rate peaked at 2.1 per 100,000 in early January 2021, declined to 0.6 per 100,000 in mid-March, and rose to 1.3 per 100,000 in April.



Using that peak hospitalization rate of 2.1 per 100,000 (or 21 per million) in this age group, and assuming the risk for myocarditis is 0.146 percent among COVID-positive patients, we get a myocarditis-from-COVID rate among adolescents of 0.03 per million. That’s a far cry from the normal background rate of four cases per million, so the risk of getting myocarditis from SARS-CoV-2 infection is probably quite small.



Now, assuming the COVID hospitalization rate for adolescents is 21 per million, and we have 73.1 million adolescents, we could expect there to be 1,535 hospitalizations for COVID in this age group in a year. If 0.146 percent of those 1,535 teens develop myocarditis, we could expect 2.2 cases of myocarditis to occur in this age group each year, among those who come down with COVID.



In summary, based on CDC statistics, we could expect just over two teens to contract myocarditis from COVID-19 infection. Meanwhile, we have 1,475 cases reported following the COVID jab in just six months (shots for 12- to 17-year-olds were authorized July 30, 2021).



Taking into account underreporting, the real number could be anywhere between 7,375 and 59,000—again, in just six months! To estimate an annual rate, we’d have to double it, giving us anywhere from 14,750 to 118,000 cases of myocarditis. So, is it actually true that “For adolescents and young adults, the risk of myocarditis caused by COVID infection is much higher than after mRNA vaccination”? I doubt it.



Can You Lessen the Damaging Effects?

There is absolutely no medical rationale or justification for children and teens to get a COVID shot. It’s all risk and no gain. If for whatever reason your son or daughter has already received one or more jabs, and you hope to lessen their risk of cardiac and cardiovascular complications, there are a few basic strategies I would suggest implementing.



Keep in mind these suggestions DO NOT supersede or cancel out any medical advice they may receive from their pediatrician. These are really only recommendations for when there are no adverse symptoms. If your child experiences any symptoms of a cardiac or cardiovascular problem, seek immediate medical attention.

First and foremost, do not give them another shot or booster.
Measure their vitamin D level and make sure they take enough vitamin D orally and/or get sensible sun exposure to make sure their level is between 60 ng/mL and 80 ng/ml (150 to 2000 nmol/l).
Eliminate all vegetable (seed) oils in their diet. This involves eliminating nearly all processed foods and most meals in restaurants unless you convince the chef to only cook with butter. Avoid any sauces or salad dressings as they are loaded with seed oils. Also avoid conventionally raised chicken and pork as they are very high in linoleic acid, the omega-6 fat that is far too high in nearly everyone and contributes to oxidative stress that causes heart disease.
Consider giving them around 500 milligrams per day of NAC, as it helps prevent blood clots and is a precursor for the important antioxidant glutathione.
Consider fibrinolytic enzymes that digest the fibrin that leads to blood clots, strokes and pulmonary embolisms. The dose is typically two to six capsules, twice a day, but must be taken on an empty stomach, either an hour before or two hours after a meal. Otherwise, the enzymes will merely act as a digestive enzyme rather than digesting fibrin.
References
Louisiana Health and Welfare Committee Meeting, Dec. 6, 2021

Louisiana Government Archived Videos 2021 (see Health and Welfare)

OpenVAERS Data as of Dec. 17, 2021

Dare to Seek the Truth Dr. Peter McCullough

SteveKirsch.substack, Dec. 30, 2021

Journal Pre-proof, A Report on Myocarditis Adverse Events in the U.S. Vaccine Adverse Events Reporting System (VAERS) in Association with […]

Census.gov 2020 Statistics

OpenVAERS Myocarditis cases by age as of Dec. 17, 2021

CDC MMWR Sept. 3, 2021; 70(35);1228–1232

CDC MMWR Aug. 6, 2021; 70(31);1053-1058

From Mercola.com


Views expressed in this article are the opinions of the author and do not necessarily reflect the views of The Epoch Times.



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« Last Edit: January 18, 2022, 12:16:04 PM by G M »

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ET: VAERS analysis censored
« Reply #329 on: January 19, 2022, 02:01:30 PM »
Researcher Calls Out Censorship After Journal Pulls COVID-19 Vaccine Adverse Events Analysis
By Petr Svab January 19, 2022 Updated: January 19, 2022biggersmaller Print
Jessica Rose didn’t ask for any of this. She started to analyze data on adverse reactions after COVID-19 vaccines simply as an exercise to master a new piece of software. But she couldn’t ignore what she saw and decided to publish the results of her analysis. The next thing she knew, she was in a “bizzarro world,” she told The Epoch Times.

A paper she co-authored based on her analysis was withdrawn by the academic journal Elsevier under circumstances that raised eyebrows among her colleagues. The journal declined to comment on the matter.

Rose received her PhD in computational biology from the Bar-Ilan University in Israel. After finishing her post-doctoral studies on molecular dynamics of certain proteins, she was looking for a new challenge. Switching to a new statistical computing software, she was looking for an interesting data set to sharpen her skills on. She picked the Vaccine Adverse Event Reporting System (VAERS), a database of reports of health problems that have occurred after a vaccination and may or may not have been caused by it.

CCP virus vaccine scotland uk
A nurse administers a CCP virus vaccine to a health and care staff member at the NHS Louisa Jordan Hospital in Glasgow, Scotland, on Jan. 23, 2021. (Jane Barlow/PA)
She said she wasn’t looking for anything in particular in the data.

“I don’t go in with questions,” she said.

What she found, however, was disturbing to her.

VAERS has been in place since 1990 to provide an early warning signal that there might be a problem with a vaccine. Anybody can submit the reports, which are then checked for duplicates. They are largely filed by health care personnel, based on previous research. Usually, there would be around 40,000 reports a year, including several hundred deaths.

But with the introduction of the COVID-19 vaccines, VAERS reports went through the roof. By Jan. 7, there were over a million reports, including more than 21,000 deaths. Other notable issues include over 11,000 heart attacks, nearly 13,000 cases of Bell’s palsy, and over 25,000 cases of myocarditis or pericarditis.

Rose found the data alarming, only to realize authorities and even some experts were generally dismissing it.

“Clearly, there’s no concern [among these authorities and experts] for people who are suffering adverse events,” she said.

The usual arguments against the VAERS data have been that it’s unverified and unreliable.

Rose, however, sees such arguments as irrelevant—VAERS was never meant to provide definitive answers, it’s meant to give early warning and, as she sees it, it’s doing just that.

“It’s emitting so many safety signals and they’re being ignored,” she said.

Epoch Times Photo
A screenshot of the homepage of the Vaccine Adverse Event Reporting System (VAERS), which is co-sponsored by the CDC, FDA, and HHS. (Screenshot/The Epoch Times)
She teamed up with Peter McCullough, an internist, cardiologist, and epidemiologist, to write a paper on VAERS reports of myocarditis in youth—an issue already acknowledged as a side effect of the vaccination, though usually described as rare.

As of July 9, they found 559 VAERS reports of myocarditis, 97 among children ages 12–15. Some of them may have been related to COVID itself, which can also cause heart problems, but there were too many cases to dismiss the likelihood the vaccines were involved, according to the authors.

“Within 8 weeks of the public offering of COVID-19 products to the 12–15-year-old age group, we found 19 times the expected number of myocarditis cases in the vaccination volunteers over background myocarditis rates for this age group,” the paper said.

After two weeks, on Oct. 15, the paper disappeared from the Elsevier website, replaced by a notice of “Temporary Removal.” Not only weren’t the authors told why, they weren’t informed at all, according to Rose.

“It’s unprecedented in the eyes of all of my colleagues,” she said.

When they brought up the issue with the journal, they were first told the paper was pulled because it wasn’t “invited,” Rose said. That was shot down as irrelevant by McCullough, who threatened to sue for breach of contract. The journal then turned to its terms of use, saying it has the right to refuse any paper for any reason.

Epoch Times Photo
Jessica Rose. (Courtesy of Jessica Rose)
It’s still not clear why the paper was pulled.

“I do apologise, but Elsevier cannot comment on this enquiry,” said Jonathan Davis, the journal’s communications officer, in an email to The Epoch Times.

In late November, the paper was replaced by a notice that the “article has been withdrawn at the request of the author(s) and/or editor.”

“It just feels like weird censorship that isn’t really justified,” Rose said.

The paper’s conclusions are not necessarily controversial. A recent Danish study concluded, for example, an elevated risk of myocarditis for young people following the Moderna COVID vaccine.

It’s common, however, even for papers that examine potential issues with the vaccines to frame their results in a way that still endorses vaccination.

“That’s what you have to say to get your work published these days,” Rose said.

Her paper did no such thing.

“As part of any risk/benefit analysis which must be completed in the context of experimental products, the points herein must be considered before a decision can be made pertaining to agreeing to 2-dose injections of these experimental COVID-19 products, especially into children and by no means, should parental consent be waived under any circumstances to avoid children volunteering for injections with products that do not have proven safety or efficacy,” the paper said.

The paper also called the vaccines “injectable biological products”—a reference to the fact that they are distinct from all other traditional vaccines.

A traditional vaccine uses “whole live or attenuated pathogens” while the COVID vaccines use “mRNA in lipid nanoparticles,” Rose explained via email. She said the lipid nanoparticles include “cationic lipids which are highly toxic.” Pfizer, the manufacturer of the most popular COVID-19 vaccine in many countries, addressed the issue by saying the dose is sufficiently low to ensure “an acceptable safety margin,” according to the European drug authority, the Committee for Medicinal Products for Human Use (pdf).

Rose also noted that the COVID-19 vaccines haven’t gone “through the 10-15 years of safety testing that vaccines have always had to go through … for obvious reasons.”

By this point, Rose is no longer a dispassionate observer. Reading through countless VAERS reports gave her a window into the hardships of those who believe they’ve been harmed by the vaccines.

“I speak for all of those people,” she said.

Epoch Times Photo
An internal medicine resident sits in a waiting area before receiving a dose of the Pfizer-BioNTech COVID-19 vaccine at a hospital in Aurora, Colorado, on Dec. 16, 2020. (Michael Ciaglo/Getty Images)
In the past, 50 reports of deaths in VAERS would prompt authorities to hit the breaks and investigate, Rose said. In her view, that should have happened with the COVID-19 vaccines a year ago.

Not only has that not happened, but it isn’t even clear what would be enough to convince the authorities to do so.

“What’s the cut-off number for the number of deaths?” Rose asked.

The counterargument is that the vaccines save more lives than they cost. But in Rose’s view, this logic is flawed since the vaccines haven’t been around long enough and studied thoroughly enough to tell how many lives they may cost.

It is known, however, that VAERS understates adverse events following vaccination—by a factor of anywhere between 5 and as much as 100, based on some estimates.

Submitting a VAERS report takes about 30 minutes and many medical practitioners simply don’t have the time, Rose said. Some may feel that filing the report may get them labeled as “anti-vaxxers.” Some may simply not associate whatever health issue they’re facing with the vaccination. Some may not even be aware VAERS exists.

It’s unlikely that any significant number of the reports would be fraudulent, she suggested, noting it’s a federal offense to submit a false report.

Rose has now joined the ranks of dissident doctors and researchers skeptical of the official line on the vaccines and the pandemic in general. She described it as something she’s compelled to do despite the disincentives involved.

“We don’t want to be doing this. But it is our duty. Doctors swore an oath to do no harm. And researchers with integrity cannot look away from this,” she said via email.

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ET: England takes the lead
« Reply #330 on: January 19, 2022, 03:30:54 PM »
second

England Ends All COVID Passports, Mask Mandates, Work Restrictions
By Lily Zhou January 19, 2022 Updated: January 19, 2022biggersmaller Print
Restrictions including COVID-19 passes, mask mandates, and work-from-home guidance will be removed in England, UK Prime Minister Boris Johnson announced on Wednesday.

Johnson also suggested that self-isolation rules may also be thrown out at the end of March as the CCP (Chinese Communist Party) virus pandemic becomes endemic.

Effective immediately, the UK government is no longer asking people to work from home.

The COVID pass mandate for nightclubs and large events won’t be renewed when it expires on Jan. 26.

Also from Jan. 27, indoor mask-wearing will no longer be compulsory anywhere in England.

The requirement for secondary school pupils to wear masks during class and in communal areas will be lifted on Jan. 20. The Department for Education is expected to update its national guidance soon.

Health Secretary Sajid Jajid will also announce plans to ease restrictions on care home visits in the coming days.

Roaring cheers from lawmakers could be heard in the House of Commons following Johnson’s announcements on masks.

Epoch Times Photo
Prime Minister Boris Johnson speaks during Prime Minister’s Questions in the House of Commons, London, on Jan. 19, 2022. (House of Commons/PA)
People who test positive for COVID-19 and their unvaccinated contacts are still required to self-isolate, but Johnson said he “very much expect not to renew” the rule when the relevant regulations expire on March 24.

“As COVID becomes endemic, we will need to replace legal requirements with advice and guidance, urging people with the virus to be careful and considerate of others,” the prime minister said.

Asked to remove testing rules for vaccinated UK-bound travellers, Johnson said the government is reviewing the testing arrangements on travel and that an announcement can be expected in the coming days.

But he refused to reconsider the vaccination mandate for frontline health care workers, insisting “the evidence is clear that health care professionals should get vaccinated.”

Johnson told MPs that the Cabinet decided to remove its so-called “Plan B” measures on Wednesday morning as data suggest the Omicron wave has peaked nationally, and he attributed stabilising hospital admission numbers to “the extraordinary booster campaign” and the public’s compliance to the restriction measures.

The removal of the “Plan B” measures against the CCP virus came as the prime minister battles increasing pressure calling for him to resign over alleged lockdown-breaching parties in Number 10 Downing Street, the prime minister’s official residence, during the pandemic.

It also came after Number 10 received a petition on Monday signed by more than 200,000 people, calling for an end to vaccine passports and similar COVID certifications.

A separate petition calling on the reversal of vaccine mandates for health care workers, which was also delivered to Number 10 on Monday, received about 160,000 signatures.

Governments in Scotland and Wales have also announced the removal of Omicron curbs, but mandatory indoor mask-wearing and COVID passes will remain in place.

Correction: Mandatory indoor mask-wearing will be lifted on Jan. 27. The Epoch Times regrets the error.


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ClotShot only or Die!
« Reply #332 on: January 20, 2022, 11:26:36 AM »
http://ace.mu.nu/archives/397474.php

Anyone see any issues with this?




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Ireland defeats Medical Fascism
« Reply #336 on: January 21, 2022, 05:53:04 PM »
Ireland to End Most CCP Virus Restrictions, Including COVID Passport
By Lily Zhou January 21, 2022 Updated: January 21, 2022biggersmaller Print
Almost all CCP (Chinese Communist Party) virus restrictions in Ireland will end on Saturday, including domestic COVID-19 Certificates, curfews, social distancing, and capacity limits.

Addressing the nation following the recommendation to lift the restrictions from the National Public Health Emergency Team, Taoiseach (Irish Prime Minister) Micheál Martin declared it’s time for the Irish to “be ourselves again.”

This makes Ireland the second country following England to remove mandatory vaccine passports after they were implemented.

But the mask mandate, self-isolation rules, and protective measures in schools will remain, and Martin “strongly encourage[d]” people to get themselves and their children vaccinated.

After a Cabinet meeting on Friday afternoon, Martin said the Coalition government agreed to lift most of the restrictions the next day.

“Humans are social beings and we Irish are more social than most. As we look forward to this spring, we need to see each other again. We need to see each other smile. We need to sing again,” he said.

“As we navigate this new phase of COVID, it is time to be ourselves again.”

The Taoiseach said people’s trust in the government is a “precious and powerful,” yet “fragile” thing that requires “confidence that the government will do what is needed in an emergency,” as well as knowing “their government will not impose restrictions on their personal freedoms for any longer than is necessary.”

From 6 a.m. on Saturday, COVID certificates, which are currently required as proof of vaccination or recovery to access indoor hospitality venues, cinemas, theatres, gyms, and leisure centres, will be scrapped.

Premises will no longer have to manage people’s movements, group sizes, and distances, and the 8 p.m. curfew for hospitality businesses and indoor events will be lifted.

Restrictions on private indoor meetings (up to four families) and capacity limits for events and weddings will also be removed.

However, mask-wearing will still be required on public transport for those aged 9 and over, in schools for children in third class and above, and in most indoor public spaces for those aged 13 and over, unless food and drinks are being consumed.

The testing and isolation guidance for people with CCP virus symptoms, positive cases, and their contacts remain the same.

The mask mandate and testing and isolation guidance will be reviewed in mid-February, by which time Martin estimates children aged between 5 and 11 “will have had the opportunity to be fully vaccinated.”

In Ireland, all over-16s have been offered a booster dose of a CCP virus vaccine, and children aged between 5 and 15 have been offered one dose.

The rules on international travels also remain unchanged, with all arrivals required to show proof of vaccination, recovery, or negative PCR test results.

The Taoiseach went on to say that “a number of key supports particularly the employment wage subsidy scheme” will be extended to support the recovery of society.

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Re: Ireland defeats Medical Fascism
« Reply #337 on: January 21, 2022, 05:55:38 PM »
Time to pivot to WWWIII

Ireland to End Most CCP Virus Restrictions, Including COVID Passport
By Lily Zhou January 21, 2022 Updated: January 21, 2022biggersmaller Print
Almost all CCP (Chinese Communist Party) virus restrictions in Ireland will end on Saturday, including domestic COVID-19 Certificates, curfews, social distancing, and capacity limits.

Addressing the nation following the recommendation to lift the restrictions from the National Public Health Emergency Team, Taoiseach (Irish Prime Minister) Micheál Martin declared it’s time for the Irish to “be ourselves again.”

This makes Ireland the second country following England to remove mandatory vaccine passports after they were implemented.

But the mask mandate, self-isolation rules, and protective measures in schools will remain, and Martin “strongly encourage[d]” people to get themselves and their children vaccinated.

After a Cabinet meeting on Friday afternoon, Martin said the Coalition government agreed to lift most of the restrictions the next day.

“Humans are social beings and we Irish are more social than most. As we look forward to this spring, we need to see each other again. We need to see each other smile. We need to sing again,” he said.

“As we navigate this new phase of COVID, it is time to be ourselves again.”

The Taoiseach said people’s trust in the government is a “precious and powerful,” yet “fragile” thing that requires “confidence that the government will do what is needed in an emergency,” as well as knowing “their government will not impose restrictions on their personal freedoms for any longer than is necessary.”

From 6 a.m. on Saturday, COVID certificates, which are currently required as proof of vaccination or recovery to access indoor hospitality venues, cinemas, theatres, gyms, and leisure centres, will be scrapped.

Premises will no longer have to manage people’s movements, group sizes, and distances, and the 8 p.m. curfew for hospitality businesses and indoor events will be lifted.

Restrictions on private indoor meetings (up to four families) and capacity limits for events and weddings will also be removed.

However, mask-wearing will still be required on public transport for those aged 9 and over, in schools for children in third class and above, and in most indoor public spaces for those aged 13 and over, unless food and drinks are being consumed.

The testing and isolation guidance for people with CCP virus symptoms, positive cases, and their contacts remain the same.

The mask mandate and testing and isolation guidance will be reviewed in mid-February, by which time Martin estimates children aged between 5 and 11 “will have had the opportunity to be fully vaccinated.”

In Ireland, all over-16s have been offered a booster dose of a CCP virus vaccine, and children aged between 5 and 15 have been offered one dose.

The rules on international travels also remain unchanged, with all arrivals required to show proof of vaccination, recovery, or negative PCR test results.

The Taoiseach went on to say that “a number of key supports particularly the employment wage subsidy scheme” will be extended to support the recovery of society.

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Follow the shifting narrative
« Reply #338 on: January 22, 2022, 12:01:50 PM »

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ET: Pandemic lessons learned; rushed vaxxes
« Reply #339 on: January 22, 2022, 04:19:06 PM »
andemic Lessons Learned: Rushed COVID Vaccines
Joe Wang
Joe Wang
 January 22, 2022 Updated: January 22, 2022biggersmaller Print
Commentary

I was a young vaccine research scientist when SARS-CoV-1 emerged in China and spread around the world in 2003, killing 811 people. Our team jumped on the newly available SARS-CoV genomic sequence, applying the then state-of-the-art bioinformatics tools to design a vaccine against the disease. In the end, the project did not move forward as the disease eventually disappeared.

Seventeen years later, when SARS-CoV-2 emerged, I had already moved on to a new career. Like a retired baseball player watching the World Series, I could not help but call balls and strikes on what was going on.

Of course, what we have witnessed so far is quite remarkable. Brilliant scientists, using today’s even more advanced technologies, developed vaccines against COVID-19 with lightning speed. It was truly a miracle that a vaccine could be developed, manufactured, and delivered to people in less than a year after the genome sequence of the particular virus was published. This is like hitting grand slams in every inning to win Game 1.

Game over! We won! I remember the excitement when the first vaccines were rolled out in early 2021. Politicians and health experts exclaimed, “Vaccines are our only way out of this pandemic,” and “When enough people are vaccinated, we reach herd immunity. We may need a 60 percent, 70 percent, even 80 percent vaccination rate to achieve that.”

We now have a more complete picture after a year-long push for vaccination. The quickly developed vaccines did not provide the anticipated protection, even in countries with a more than 90 percent vaccination rate, such as Israel. Now we’re being told to get boosted, to get a third and even a fourth dose. Some are saying new booster shots should be given every six months, while others say different vaccines are necessary for different variants.

It’s becoming clear now that the available vaccines are not the way out of the pandemic—as they were initially touted to be—and trust in public health authorities is eroding.

What went wrong?

Where COVID Vaccine Design Falls Short
In 2003, our team examined the whole genome of SARS-CoV-1 and modelled the selection of antigens from the virus against different types of anticipated human immune responses. Our vaccine candidates did not get into testing, but the designed effect was that the vaccine, once inoculated, would work with the immune system to stimulate the desired responses to generate strong and lasting protection against future SARS-CoV-1 infections.

Epoch Times Photo
A freeway sign displaying a COVID-19 message shines above the 5 Freeway in Los Angeles, Calif., on Jan. 20, 2022. (John Fredricks/The Epoch Times)
The human body is really remarkable, a close to perfect creation with an amazingly sophisticated immune system. It consists not only of short-term defence mechanisms (such as antibody-producing B cells) that can be mounted quickly to destroy invaders, but also has long-term memory T cells and memory B cells to provide sometimes life-long immunity in case the pathogen invades again.

Unlike drugs that are prescribed to treat the sick, vaccines are for healthy people to prevent diseases from happening. Vaccines should be taken in an orderly fashion, with informed consent and without political, social, or emotional pressure, unless there is an emergency.

COVID-19 was regarded as an emergency, so the U.S. Food and Drug Administration skipped the approval process for use of the newly developed vaccines under Emergency Use Authorization. It can be said that the designs of the spike protein-based vaccines were also rushed. The COVID-19 vaccines are the only vaccines in history that were developed and distributed in the midst of a pandemic. All the other vaccines took years to be designed, tested, and approved.

Previously, when designing a vaccine, although short-term protection was welcome, long-term immune response was always the top priority. The most important immune response that a vaccine must induce is the memory T cell response.

Today, the most widely used SARS-CoV-2 vaccines are Pfizer-BioNTech’s BNT162b2, Moderna’s mRNA-1273, and Johnson & Johnson’s Janssen JNJ-78436735 vaccines. Without exception, they are all solely based on SARS-CoV-2’s spike protein, or S protein.

The spike protein is an obvious choice as it is the most exposed viral protein, ideal as a vaccine candidate. It is totally understandable that, when pressured by the Trump administration’s Operation Warp Speed, these companies designed their vaccines using the spike protein, without testing the specific immune response, especially memory T cell responses that the S protein stimulates. Necessary steps to assure the safety and efficacy of the vaccines were shortened significantly using educated guesses—instead of real data from tests—in order to get the vaccines to market in months instead of years.

However, assumptions, even educated assumptions, simply cannot replace testing.

Epoch Times Photo
People arrive to be vaccinated at the New South Wales Health mass vaccination hub at Homebush in Sydney, Australia, on Aug. 23, 2021. (Lisa Maree Williams/Getty Images)
It shouldn’t come as a surprise, then, that these rushed vaccines failed to behave the way they were supposed to. When reports emerged showing waning protection after six months of vaccination, it became evident that the design of the vaccines was not ideal.

The assumption that the S protein induces memory T cell response is wrong.

On Jan. 10 this year, Nature Communications published the peer-reviewed article, “Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts.” The authors presented data showing a very “limited protective function of spike-cross-reactive T cells.” This explains why today’s three most popular vaccines all provide good protection in the short term, and only in the short term.

The S protein vaccine strategy, albeit an obvious choice, is now proven to be lacking. “S” stands for short-lived, short-term, and, unfortunately, short-sighted. The spike-protein-only vaccines were rushed.

This is not to diminish the incredible job the vaccines did in the short term to protect lives when no other effective protection was available. It would have been so much better, though, if the vaccine manufacturers had included SARS-CoV-2’s N protein (nucleocapsid), for example, as well as the S protein in their vaccine design.

It is time now for vaccine developers and public health authorities to take a deep breath, calmly evaluate the well-researched data currently available, and endeavour to provide the public with answers to the following questions:

Given the immunity already established by the widespread natural infections of all the variants, and the large-scale vaccinations, should the authorities continue pushing vaccine mandates with the existing, less perfect, rushed vaccines?
Like the seasonal flu, if there is a need for a new generation of SARS-CoV-2 vaccines to reduce serious cases in a future endemic situation, what mechanisms are in place to ensure the rushed vaccines approach is not repeated?
Every vaccine has side effects. What are the side effects of the existing vaccines, and what safety measures will be in place to minimize such side effects in the next generation of vaccines?
It takes a team and different skills to win a game. Hitting grand slams in the first game is a good thing, but it would not necessarily win you the World Series. The first generation of SARS-CoV-2 vaccines has accomplished its mission. Now, the vaccination-only approach should give way to a holistic approach of managing the upcoming endemic phase of SARS-CoV-2. As we say goodbye to the pandemic, we should also bid farewell to vaccine mandates and lockdowns.

More importantly, when the next devastating infectious agent (not necessarily a coronavirus) arrives, our political and medical leaders need to be more level-headed and even-handed in their approach, and enable the populace to navigate the storm without a heavy loss of life from the disease or from missteps in crisis management policies.

Views expressed in this article are the opinions of the author and do not necessarily reflect the views of The Epoch Times.

Joe Wang
Joe Wang
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Joe Wang, Ph.D., was a lead scientist for Sanofi Pasteur’s SARS vaccine project in 2003. He is now the president of New Tang Dynasty TV (Canada), a media partner of The Epoch Times.

G M

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Fighting for freedom in Soviet Canuckistan
« Reply #340 on: January 23, 2022, 08:13:41 AM »
https://bittercenturion.blogspot.com/2022/01/disconnect.html?m=1

January 22, 2022
DISCONNECT
 Well, well, well....apparently the tide is turning on the politicians, media pundits, so-called 'experts', and other assorted asswipes and idiots that managed to convince the entire planet that everyone was going to die and absolutely, positively, without a doubt HAD to submit to their 'masters' in government and have an experimental mRNA substance injected into their bodies.

It seems people have not only caught on that they were lied to the entire time, clued in by the constantly shifting narrative and goalposts, but also that the substance they injected into themselves all willy-nilly not only doesn't work in protecting them from the virus or spreading it to others, no matter how many doses you take, but does, in fact, actually destroy their immune system - revelations only known now thanks to the several dozens of bona fide doctors and scientists - leaders in their chosen disciplines - who cared more about the integrity of their chosen professions than the money taken by their contemporaries that turned them into whores.

That, unfortunately, is going to be a massive kick in the dick for a lot of people.  I've read on another blog, probably Busted Knuckles, that the black pill is the hardest one to swallow.  He wasn't fucking kidding. 

I'm not sure how I feel about it, personally, especially since A LOT of people I know (family, acquaintances, and coworkers) not only told me I was insane for trying to warn them of what they're only finding out now, but I'm fairly certain wouldn't have had any problems with the 'unclean', like my kids and I, mercilessly thrown into fucking internment camps.  The compassionate side of me, which I don't think is completely dead, would like to hope that there's a cure for what's been done to these people.  That maybe they could be saved and given a second chance.  That maybe they've seen the error of their ways.

On the other hand?  For some of them, ESPECIALLY the ones I personally witnessed cruelty and condemnation from, towards people who didn't take the clot shot?  Thoughts and prayers, fuckers.

Amid all this, I happened to catch a small clip, courtesy of Paul Joseph Watson:

https://www.youtube.com/watch?v=l5iG-728tDw

 Holy fucking crap.  Seriously?
 

 In the clip, this intellectually bankrupt harpy, Ngaire Woods (who happens to be a professor at Oxford) goes on to say the elites get along and trust each other, but the commoners don't trust them in every single country where they operate.

Really?  Now why the hell do you think that is, Ngaire??  Could it be because, for decades, you and people like you have been lying to, cheating, and stealing from us 'common folk'?  Could it have anything to do with the fact that you barely regard us as human beings, if you bother to pay attention at all?  Do you suppose it could have anything to do with how pretty much EVERY DAMN THING you people do is at the expense of common people?  I mean, Jesus tap dancing Murphy...you even refer to yourselves as the 'elite'.  Self aware much?

I wonder if it ever once occurred to these people to, even once, put themselves in the shoes of a commoner and ask themselves what it would be like to live under the 'rules' and 'policies' that they expect everybody else but them to live under?  I know, I know....of course they didn't.

I'm a HUGE fan of the Raging Dissident podcast up here in Canada - never miss a show and I HIGHLY recommend it (https://ragingdissident.com/).  Recently, he did a rant on something that I'd been saying for years: there are no 'left' or 'right' wings.  It's the common people vs. these uber wealthy, uber powerful bastards who spend immense amounts of time and money getting the commoners to fight over bullshit like political ideology, religion, and whatever else they can conjure up so that WE aren't paying attention to how hard THEY continue to fuck with us.  These people don't give a rusty fuck about any of us, no matter who we vote for, what God we worship, what brand of laundry detergent we use, none of it.  They fucking hate us, that much should be obvious by now.

And they're actually so fucking stupid, despite all their education and experience that supposedly makes them oh-so-better than us proles, they can't even understand why WE don't trust them. 

Consider the COVID-19 narrative.  You want to know why it's falling apart?  Because they're not very smart people.  They decided to use GOVERNMENT to administer and carry out their plans with the pandemic.  Government - the most bottom shelf, half-assed, inefficient, bloated, and wasteful institution on the planet; they were counting on this to carry out THEIR plans to do....shit, I don't even know anymore.  Bring about a Central Bank Digital Currency (CBDC)? De-populate the planet? Bring about a social credit system?  Could be any of these things, all of them, or none of them.  I don't know and I don't care.  I DO know they weren't being honest and I knew that all along, which is precisely why I went along with NONE of it.

But they counted on the grossly incompetent and profoundly ignorant governments of the world (particularly the developed world) to carry out these plans and, true to form, they fucked it up.  These 'elites' are the worst example of the Dunning-Kruger effect I have ever seen.  They're dumb and they suck, and everybody knows it except them because they're dumb and they suck.

 Right now, there's a massive convoy of truckers and supporters heading to Ottawa to confront Prime Minister Blackface over his bullshit vaccine mandates.  At the time of this writing, these guys have raised well over a million and a half dollars since Wednesday afternoon.  They're showing the balls and the honour that a good deal of our so-called 'heroes' in law enforcement and the military SHOULD have shown, but couldn't be bothered to, instead leaving assholes like me to stand alone.

I hope these guys succeed.  I hope they force a stop to these fucking mandates and I hope they topple this corrupt government in every way that the majority of apathetic, lazy, mouth breathing assholes in this country couldn't in THREE goddamn elections. I don't think they're gonna back down. Prime Minister Blackface basically kicked a tiger in the balls here. He'd better have a plan to deal with the teeth.

Show some support to these truckers, if you can.  They're not doing this to 'throw a tantrum' or because they're 'afraid of a needle' - comments I've seen from a lot of gutless scumbags on social media.  They're doing it because, despite what the artsy-fartsy 'intellectual' crowd tends to think of blue collar working folks, they ARE the salt of the earth, they're much more intelligent than they're given credit for, have a wealth of life experience, and believe it or not, they give a damn about our country and our rights and liberties. Rights and liberties these clueless 'elites' would rather we not had.

They deserve our support and respect.


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Funny how hard they tried to hide this…
« Reply #343 on: January 24, 2022, 11:10:40 AM »
http://ace.mu.nu/archives/397540.php

Why are they so desperate to push the ClotShot?

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NY State judge strikes down Gov. Hochul's mandate on Sep of Powers grounds.
« Reply #344 on: January 24, 2022, 07:22:41 PM »
New York Judge Strikes Down Governor Hochul’s Mask Mandate
By BRITTANY BERNSTEIN
January 24, 2022 8:03 PM


New York Governor Kathy Hochul delivers the State of the State address in the Assembly Chamber at the state Capitol in Albany, N.Y., January 5, 2022. (Hans Pennink/Pool via Reuters)

A New York State Supreme Court judge on Monday ruled that Governor Kathy Hochul’s mask mandate for schools and other public locations is unconstitutional.

Judge Thomas Rademaker found that the governor and the state health commissioner did not have the authority to enact a mask mandate without the state legislature, given that the governor no longer has emergency powers.

The mask mandate has been in place since mid-December, when the state saw a surge in the highly transmissible Omicron variant.

“There can be no question that every person in this State wishes, wants and prays that this era of COVID ends soon and they will surely do their part to see that is accomplished,” Rademaker wrote in his decision. “However, enacting any laws to this end is entrusted solely to the State Legislature. While the intentions of Commissioner Bassett and Governor Hochul appear to be well aimed squarely at doing what they believe is right to protect the citizens of New York State, they must take their case to the State Legislature.”

The ruling comes from a state Supreme Court based in Nassau County, which is a trial court. The New York Court of Appeals is akin to a more traditional “Supreme Court” in terms of authority, in that it is the state’s highest court.

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In a statement Monday evening, Hochul vowed to appeal the ruling.

“My responsibility as Governor is to protect New Yorkers throughout this public health crisis, and these measures help prevent the spread of COVID-19 and save lives,” Hochul said. “We strongly disagree with this ruling, and we are pursuing every option to reverse this immediately.”

The ruling comes weeks after Nassau County’s newly sworn-in Republican county executive issued an order allowing school districts to decide whether to institute mask mandates, in defiance of Hochul’s order.

“School boards are comprised of elected officials who make decisions based upon the unique circumstances of each district,” county executive Bruce Blakeman said at a press conference at the time. “They are in the best position to make these decisions, not an autocracy in Albany.”

Blakeman also issued orders to formalize his decision not to enforce the governor’s mask mandates that he said “unfairly fine residents and small businesses thousands of dollars” and also allow public county workers to go maskless indoors.

The county executive celebrated the ruling in a tweet on Monday: “A NYS Supreme Court Judge has ruled that the Governor’s mask mandate is illegal. The Governor and State Education Department have NO authority to enforce this mandate without the approval of State lawmakers. This is a major win for students & parents.”



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Re: NY State judge strikes down Gov. Hochul's mandate on Sep of Powers grounds.
« Reply #347 on: January 25, 2022, 03:27:57 PM »
Laws don’t apply to dems.

http://ace.mu.nu/archives/397562.php

New York Judge Strikes Down Governor Hochul’s Mask Mandate
By BRITTANY BERNSTEIN
January 24, 2022 8:03 PM


New York Governor Kathy Hochul delivers the State of the State address in the Assembly Chamber at the state Capitol in Albany, N.Y., January 5, 2022. (Hans Pennink/Pool via Reuters)

A New York State Supreme Court judge on Monday ruled that Governor Kathy Hochul’s mask mandate for schools and other public locations is unconstitutional.

Judge Thomas Rademaker found that the governor and the state health commissioner did not have the authority to enact a mask mandate without the state legislature, given that the governor no longer has emergency powers.

The mask mandate has been in place since mid-December, when the state saw a surge in the highly transmissible Omicron variant.

“There can be no question that every person in this State wishes, wants and prays that this era of COVID ends soon and they will surely do their part to see that is accomplished,” Rademaker wrote in his decision. “However, enacting any laws to this end is entrusted solely to the State Legislature. While the intentions of Commissioner Bassett and Governor Hochul appear to be well aimed squarely at doing what they believe is right to protect the citizens of New York State, they must take their case to the State Legislature.”

The ruling comes from a state Supreme Court based in Nassau County, which is a trial court. The New York Court of Appeals is akin to a more traditional “Supreme Court” in terms of authority, in that it is the state’s highest court.

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In a statement Monday evening, Hochul vowed to appeal the ruling.

“My responsibility as Governor is to protect New Yorkers throughout this public health crisis, and these measures help prevent the spread of COVID-19 and save lives,” Hochul said. “We strongly disagree with this ruling, and we are pursuing every option to reverse this immediately.”

The ruling comes weeks after Nassau County’s newly sworn-in Republican county executive issued an order allowing school districts to decide whether to institute mask mandates, in defiance of Hochul’s order.

“School boards are comprised of elected officials who make decisions based upon the unique circumstances of each district,” county executive Bruce Blakeman said at a press conference at the time. “They are in the best position to make these decisions, not an autocracy in Albany.”

Blakeman also issued orders to formalize his decision not to enforce the governor’s mask mandates that he said “unfairly fine residents and small businesses thousands of dollars” and also allow public county workers to go maskless indoors.

The county executive celebrated the ruling in a tweet on Monday: “A NYS Supreme Court Judge has ruled that the Governor’s mask mandate is illegal. The Governor and State Education Department have NO authority to enforce this mandate without the approval of State lawmakers. This is a major win for students & parents.”

Crafty_Dog

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Re: The War with Medical Fascism
« Reply #348 on: January 26, 2022, 03:43:45 AM »
Be aware that in NY the "Supreme Court" is NOT its' supreme court, "the Court of Appeals" is, and for the moment it has just reversed this decision.  The mask mandate is back in effect.